Plasmodium falciparum is a highly lethal malaria parasite of humans. A major portion of its life cycle is dedicated to invading and multiplying inside erythrocytes. The molecular mechanisms of erythrocyte invasion are incompletely understood. P. falciparum depends heavily on sialic acid present on glycophorins to invade erythrocytes. However, a significant proportion of laboratory and field iso...

The percent identity matrices of two sequence multiple alignments between linker histones from chicken and mammalian species are described. Linker histone protein sequences for chicken, mouse, rat and humans, available on public databases were used. This information is related to the research article entitled "Identification of novel post-translational modifications in linker histones from chic...

Primary and secondary immune responses to sheep erythrocytes have been obtained in tissue cultures of dispersed mouse spleen (1, 2), and such cultures provide a means of investigating, at the cellular level, the in vitro antibody response. The results of Mosier (3) suggest that at least two different cell populations in mouse spleen suspensions are required for the primary response to sheep ery...

De Cavanagh, Elena M. V., Felipe Inserra, León Ferder, and César G. Fraga. Enalapril and captopril enhance glutathione-dependent antioxidant defenses in mouse tissues. Am. J. Physiol. Regulatory Integrative Comp. Physiol. 278: R572–R577, 2000.—The effect of enalapril and captopril on total glutathione content (GSSG 1 GSH) and seleniumdependent glutathione peroxidase (Se-GPx) and glutathione red...

The biosynthetic pathway of diphosphopyridine nucleotide has been formulated through a study of yeast autolysates, erythrocytes, and liver homogenates. Two such pathways have been described by these procedures. Each system ultimately utilizes the enzyme diphosphopyridine nucleotide pyrophosphorylase. In the first pathway, the enzyme produces diphosphopyridine nucleotide directly by coupling ade...

Erythrocytes from the same mouse strains gave similar results; here the cell number was increased to 109/ml to obtain a significant difference between curves for highand low-responder mice. It is possible that these results are affected by contamination with mouse ferritin from the spleen or plasma despite washing of cells. To minimize possible contamination by mouse ferritin, lymph-node cells,...

Activation of chicken globin gene transcription has been demonstrated in chicken erythrocyte--rat L6 myoblast heterokaryons. The globin mRNA is polyadenylylated and is translated into adult chicken alpha A-, alpha D-, and beta-globin polypeptides. No fetal globin mRNA or globin polypeptides were detected. Heterokaryons between chicken erythrocytes and mouse neuroblastoma cells or hamster BHK ce...

The direct and indirect plaque technique for the detection of antibody-forming cells against sheep erythrocytes was utilized for the investigation of a number of biological parameters of the primary and secondary immune response on a cellular level. The sequential pattern of 19S followed by 7S antibody formation was elicited in the primary response after a latent period of at least 1-2 days and...

We report here the isolation and genomic organization of the orthologous mouse Duffy gene, named Dfy. It is a single copy gene located in chromosome 1 in a region homologous to the human Duffy gene (FY). Sequence analyses indicate that Dfy consists of two exons: exon 1 of 55 nucleotides, which encodes 7 amino acid residues; and exon 2 of 1038 nucleotides, which encodes 327 residues. The single ...