zearalenone (zea) mycotoxin is a potent estrogenic metabolite. it is the primary toxin causing infertility, abortion or other breeding problems. a hplc method was validated for zea in foods using a monolithic column with sample clean-up on an immunoaffinity column. a certified reference material (crm) from fapas (uk) was analyzed. a survey of zea was performed on the 72 samples of rice, bread, ...

With a growing number of cell-based biotechnological applications, there is a need for particle separation systems capable of multiparameter separations at high purity and throughput, beyond what is presently offered by traditional methods including fluorescence activated cell sorting and column-based magnetic separation. Toward this aim, we report on the integration of microfluidic acoustic an...

This paper describes the synthesis and chromatographic and morphologic characterization of two monolithic silica nano-columns (50 µm i.d.) prepared by sol-gel processes, using hydrophilic interaction (HILIC) mode separations to evaluate their performance. Two types of monoliths were prepared by varying the precursors (tetraethoxysilane or a tetraethoxysilane-methyltrimethoxysilane mixture) and ...

A new low-cost process for fast fabrication of multilayer microfluidic devices using cyclic olefin copolymer film materials is presented. This novel process consists of the fabrication of microfluidic features by xurography, followed by multilayer lamination via cyclohexane vapor exposure. Exposure time to this solvent and compression time were optimized for bond tensile strength. A three-layer...

Distributed supervisory control is a method to synthesize local controllers in discrete-eventsystems with a systematic observation of the plant. Some works were reported on extending this methodby which local controllers are constructed so that observation properties are preserved from monolithic todistributed supervisory control, in an up-down approach. In this paper, we find circumstances in ...

Institute for Instrumentation in Molecular Imaging, I3M-CSIC, Valencia, Spain In PET detectors based on monolithic scintillators, the photon impact position can be estimated from the light intensity distribution (LD) on the photodetector pixels. Typically, there is a poor estimation of the interaction positions towards the edges when linear algorithms such as Center of Gravity (CoG) are used. W...