The introduction of mechanical functions and controlled motion based on molecular motors machines offers tremendous opportunities towards the design dynamic systems responsive materials.

mechanical stress. The diameters of the pores can be tuned between 2 and 10 nm to allow for different drug loadings. Compared with traditional oral or injectable drugs, these meso­ porous nanoparticles can enhance bioavailabil­ ity, improve therapeutic efficacy and minimize side effects [4]. At present, the key challenge in developing mesoporous nanoparticle­based DDS is designing the structure...

The conference series Machines, Computations and Universality (MCU) explores computation in the setting of various discrete models, such as Turing machines, register machines, cellular automata, tile assembly systems, rewriting systems, molecular computing models and neural models, and in the setting of analog and hybrid models, including BSS machines, signal machines and quantum computing, to ...

From the abyss of the ocean to the human gut, bacterial viruses (or bacteriophages) have colonized all ecosystems of the planet earth and evolved in sync with their bacterial hosts. Over 95% of bacteriophages have a tail that varies greatly in length and complexity. The tail complex interrupts the icosahedral capsid symmetry and provides both an entry for viral genome-packaging during replicati...

To comply with the rapidly increasing demand of information storage and processing, new strategies for computing are needed. The idea of molecular computing, where basic computations occur through molecular, supramolecular, or biomolecular approaches, rather than electronically, has long captivated researchers. The prospects of using molecules and (bio)macromolecules for computing is not withou...

Proteins are linear polymers synthesized by ribosomes from activated amino acids. The product of this biosynthetic process is a polypeptide chain, which has to adopt the unique three-dimensional structure required for its function in the cell. In 1972, Christian Anfinsen was awarded the Nobel Prize for Chemistry for showing that this folding process is autonomous in that it does not require any...

The bottom-up construction and operation of machines and motors of molecular size is a topic of great interest in nanoscience, and a fascinating challenge of nanotechnology. The problem of the energy supply to make molecular machines work is of the greatest importance. Research in the last ten years has demonstrated that light energy can be used to power artificial nanomachines by exploiting ph...

Molecular machines drive essential biological processes, with the component parts of these machines each contributing a partial function or structural element. Mitochondria are organelles of eukaryotic cells, and depend for their biogenesis on a set of molecular machines for protein transport. How these molecular machines evolved is a fundamental question. Mitochondria were derived from an alph...