Radiotherapy has an important role in the treatment of prostate cancer. Three-dimensional conformal radiation therapy (3D-CRT), intensity modulated radiation therapy (IMRT) and volumetric modulated arc therapy (VMAT) techniques are all applied for this purpose. However, the risk of secondary radiation-induced bladder cancer is significantly elevated in irradiated patients compared surgery-only ...

BACKGROUND Intensity-modulated radiation therapy (IMRT) uses solid compensators or multileaf collimators to modulate the intensity of radiation in each field, delivering highly conformal dose distributions. This technique allows treating volumes with concave shapes when the target is close to a critical structure. The movement of multileaf collimator under computer control can modulate the dose...

Homogeneous target dose distribution in intensity-modulated radiotherapy (IMRT) for sinonasal cancer (SNC) is challenging to achieve. To solve this problem, we established and evaluated a basal-dose-compensation (BDC) optimization approach, in which the treatment plan is further optimized based on the initial plans. Generally acceptable initial IMRT plans for thirteen patients were created and ...

Advancement in treatment delivery techniques in external beam radiation therapy has significantly improved the conformal radiation dose distributions to the tumor while reducing dose to the critical structures. Modern treatment techniques combined with sophisticated treatment planning systems have led to increase in the treatment planning studies in the recent years. In this article, we review ...

New advances in radiation therapy for children allow increased conformability and reduced doses to non-target tissues. We report our experience in treating a 4-year-old child with craniospinal tomotherapy after surgery of the primary tumor, a supratentorial primitive neuroectodermal tumor. The tomotherapy plan was compared with conventional craniospinal irradiation, 3D conformal radiation thera...

Although many methods exist for intensity modulated radiotherapy (IMRT) fluence map optimization for crisp data, based on clinical practice, some of the involved parameters are fuzzy. In this paper, the best fluence maps for an IMRT procedure were identifed as a solution of an optimization problem with a quadratic objective function, where the prescribed target dose vector was fuzzy. First, a d...

Background: Commissioning tests are recommended before implementing Intensity Modulated Radiation Therapy. This study evaluated five different plans of IMRT mocks for different modulation indices. Materials and Methods: IMRT tests were done in slab phantom for both 6MV and 15 MV photon energies using a 2D array ion chamber dosimeter. Results: The acceptance criteria were based on 3% /3mm. All t...

Integrated treatment planning for cancer patients has high importance in intensity modulated radiation therapy (IMRT). Direct aperture optimization (DAO) is one of the prominent approaches used in recent years to attain this goal. Considering a set of beam directions, DAO is an integrated approach to optimize the intensity and leaf position of apertures in each direction. In this paper, first, ...