PURPOSE To determine how the omission of whole brain radiotherapy (WBRT) affects the neurocognitive function of patients with one to four brain metastases who have been treated with stereotactic radiosurgery (SRS). METHODS AND MATERIALS In a prospective randomized trial between WBRT+SRS and SRS alone for patients with one to four brain metastases, we assessed the neurocognitive function using...

This paper determines to within a single measurement the minimum number of measurements required to successfully reconstruct a signal drawn from a Gaussian mixture model in the low-noise regime. The method is to develop upper and lower bounds that are a function of the maximum dimension of the linear subspaces spanned by the Gaussian mixture components. The method not only reveals the existence...

Frequency-domain equalization (FDE) based on minimum mean square error (MMSE) criterion can replace the conventional rake combining to significantly improve the bit error rate (BER) performance in a frequency-selective fading channel. MMSE-FDE requires an accurate estimate of the channel transfer function and the signal-to-noise power ratio (SNR). Direct application of pilot-assisted channel es...

We conducted a cross-sectional study to determine the distribution of cognitive functioning as measured by the Mini-Mental State Examination (MMSE) among a sample of Hispanic and non-Hispanic White (NHW) residents from two counties in rural, southern Colorado. Residents aged 60 years and older (N = 1,360) were administered the full MMSE, a sociodemographic and medical interview. Protocols were ...

This paper investigates optimum and sub-optimum linear Minimum Mean Square Error (MMSE) Multi-User Detection (MUD) techniques for multi-carrier code division multiple access transmission systems. In a first step, we present two formulations of MMSE MUD techniques that are optimum for any number of users and any power distribution and achieve exactly the same performance with a different computa...

Frequency-domain equalization (FDE) based on the minimum mean square error (MMSE) criterion can replace the conventional rake combining while offering significantly improved bit error rate (BER) performance for the downlink DS-CDMA in a frequency-selective fading channel. However, the presence of residual inter-chip-inference (ICI) after FDE produces orthogonality distortion among the spreading...