Approximately a third of patients with suspected gastro-oesophageal reflux disease are resistant or partial responders to proton pump inhibitors (PPIs). Many of these patients do not have gastro-oesophageal reflux disease, but suffer from functional heartburn or dyspepsia. The potential mechanisms underlying failure of PPI treatment in patients with reflux-related symptoms include persistence o...

Ambient temperature vacuum distillation in conjunction with headspacesolid phase microextraction (HS-SPME) was used to study the volatile compounds (VC) in Agaricus bisporus. Different extraction times 2, 3, 4 and 5 h were also tested against VC yield and 4 h was found to be the best extraction time with most of the compounds retrieved. No significant difference was found between the VC extract...

A Kalman filter (KF) estimator has been formulated using a sequence of reduced-order models representing a whole batch behavior for providing the estimates of dynamic composition in a ternary batch distillation process operated in an optimal-reflux policy. A set of full-order models is firstly obtained by linearizing around different pseudo-steady state operating conditions along batch optimal ...

A continuous melt suspension crystallization process has been presented for the purification of the phosphoric acid in this study, which is performed in the cascade of a mixed suspension mixed product removal (MSMPR) crystallizer and a gravity wash column for the subsequent solid-liquid separation. Dynamic behavior in the crystallizer and role of reflux ratio on the purification efficiency of c...

A study of the influence of distillation system, oak wood type, and aging time on volatile compounds of cider brandy was carried out. Acetaldehyde and acetaldehyde diethyl acetal were influenced by distillation technology, oak wood type, and maturation time. The majority ester, ethyl ethanoate, increased during aging, the highest level of this ester being detected in spirits distilled by double...

Chronic venous disease (CVD) is the most prevalent form of vascular disease, affecting about a third of adult Americans. Most patients present with varicose veins but swelling and skin damage are common as well. The signs and symptoms of CVD are result of venous hypertension that develops from reflux, obstruction or a combination of both. In patients with CVD, around 70-80% will have superficia...