The ovarian reserve represents the stock of quiescent primordial follicles in the ovary which is gradually depleted during a woman's reproductive lifespan, resulting in menopause. Müllerian inhibiting substance (MIS) (or anti-Müllerian hormone/AMH), which is produced by granulosa cells of growing follicles, has been proposed as a negative regulator of primordial follicle activation. Here we sho...

This research aims to investigate the relationship between performance measurement system (PMS) and management information system (MIS) adopting a company life-cycle approach. The scope is to show if and how MIS influences PMS and vice versa. The investigation is carried out using the case study methodology in Italian and Scottish small and medium enterprises (SMEs). The empirical results are s...

A methodology for conducting the case study of a management information system (MIS) is presented. Suitable for the study of a single case, the methodology also satisfies the standards of the natural science model of scientific research. This article provides an overview of the methodological problems involved in the study of a single case, describes scientific method, presents an elucidation o...

Müllerian inhibiting substance (MIS) has recently been implicated in multiple cellular functions including promotion of cell survival, but the receptor(s) and signaling pathways involved remain elusive. We have investigated the possibility of YWK-II protein, previously shown to interact physically with MIS and G(o) protein, being a receptor mediating the cell survival effect of MIS. In YWK-II-o...

The expression of Mullerian inhibiting substance (MIS), a key molecule in sex differentiation and reproduction, is tightly regulated. It has been suggested that meiotic germ cells repress MIS expression in testicular Sertoli cells, although the substance responsible for this cell-cell communication remains unknown. Here, we present the cytokine tumor necrosis factor alpha (TNF-alpha) as a stron...

BACKGROUND Much of the cancer burden in the USA is preventable, through application of existing knowledge. State-level funders and public health practitioners are in ideal positions to affect programs and policies related to cancer control. Mis-implementation refers to ending effective programs and policies prematurely or continuing ineffective ones. Greater attention to mis-implementation shou...

This paper discusses what is needed to make MIS into a coherent research field. It defines 3 main needs: 1. Clarification of reference disciplines. 2. Definition of the dependent variable. 3. Building a cumulative tradition. It reviews the relationship of MIS to computer technology and to practice and assess the publishing inlets for MIS

Having recently moved from the business world to academia, my impressions regarding MIS research changed. Initially questioning the relevance of MIS research to the business community, I conclude that MIS research can be very relevant, given the use of appropriate metrics.

Background Nepal has made remarkable improvements in maternal health outcomes. The implementation of demand and supply side strategies have often been attributed with the observed increase in utilization of maternal healthcare services. In 2005, Free Delivery Care (FDC) policy was implemented under the name of Maternity Incentive Scheme (MIS), with the intention of reducing transport costs asso...

BACKGROUND For total hip arthroplasty (THA), minimally invasive surgery (MIS) uses a smaller incision and less muscle dissection than the classic approach (CLASS), and may lead to faster rehabilitation. QUESTIONS/PURPOSES Does minimally invasive hip arthroplasty result in superior clinical outcomes? PATIENTS AND METHODS In this double-blind randomized controlled trial, 120 consecutive prima...