نتایج جستجو برای: mir 15

تعداد نتایج: 541081  

Journal: :The Journal of pathology 2008
M Wang L P Tan M K Dijkstra K van Lom J-L Robertus G Harms T Blokzijl K Kooistra M B van T'veer S Rosati L Visser M Jongen-Lavrencic P M Kluin A van den Berg

Several miRNAs have been reported to be associated with immunoglobulin heavy chain (IgH) mutation and ZAP-70 expression status in blood samples of B-cell chronic lymphocytic leukaemia/small lymphocytic lymphoma (B-CLL/SLL). In the bone marrow and lymphoid tissues, proliferation centres (PCs) represent an important site of activation and proliferation of the neoplastic cells, suggesting that the...

2017
Neng Wang Xiaoxin Zheng Jin Qian Wei Yao Lu Bai Guo Hou Xuan Qiu Xiaoyan Li Xuejun Jiang

The aim of the present study was to determine if renal sympathetic denervation (RSD) may alleviate isoproterenol-induced left ventricle remodeling, and to identify the underlying mechanism. A total of 70 rats were randomly divided into control (n=15), sham operation (n=15), heart failure (HF) with sham operation (HF + sham; n=20) and HF with treatment (HF + RSD; n=20) groups. The HF model was e...

Journal: :acta physiologica hungarica 2014
xiaoying jiang

it was known that il-1β-induced rapid expression of mir-146a, which regulated the secretion of inflammatory chemokines in human a549 alveolar epithelial cells. however, little is known about the level of primary mir-146a and the downstream biogenesis of mir-146a in a549 cells. we examined the levels of primary mir-146a and mature mir-146a in a549 cells following treatment with pharmacological i...

2015
Jian Wang Guorong Dan Jiqing Zhao Yu Ding Feng Ye Huiqin Sun Fan Jiang Jin Cheng Fahuan Yuan Zhongmin Zou

BACKGROUND MicroRNA-34a (miR-34a) is a potential prognostic factor for survival in patients with several types of cancer according to previous clinical researches. We conducted a systematic review and meta-analysis to summarize the significance of increased miR-34a expression in the prognosis of patients' overall survival. MATERIALS AND METHODS The present systematic review and meta-analysis ...

2017
Ilona Hromadnikova Katerina Kotlabova Katarina Ivankova Ladislav Krofta

The aim of the study was to demonstrate that preterm birth (PTB) is associated with altered C19MC microRNA expression profile in placental tissues. Gene expression of 15 placental specific microRNAs (miR‑512‑5p, miR‑515‑5p, miR‑516‑5p, miR‑517‑5p, miR‑518b, miR‑518f‑5p, miR‑519a, miR‑519d, miR‑519e‑5p, miR‑520a‑5p, miR‑520h, miR‑524‑5p, miR‑525‑5p, miR‑526a and miR‑526b‑5p) was compared between...

Journal: :Proceedings of the National Academy of Sciences 2018

Journal: :BMC Genomics 2021

Abstract Background Colossoma macropomum (tambaqui) and Piaractus mesopotamicus (pacu) are good fish species for aquaculture. The tambacu, individuals originating from the induced hybridization of female tambaqui with male pacu, present rapid growth robustness, characteristics which have made tambacu a choice Brazilian farms. Here, we used small RNA sequencing to examine global miRNA expression...

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