Parapharyngeal space (PPS) is one of potential space of head and neck region and due to its hidden anatomical location, pathologies arising in this space are late to diagnose. This inverted pyramidal space was termed previously as pterygomaxillary space, lateral pharyngeal space and pharyngio-maxillary space. Parapharyngeal space is the current term that has come to stay because of indistinct i...

The main purpose of this study was to determine the expression of interleukins-17/-23 (ILs-17/-23) and receptors of interleukins-17/-23 (IL-17R, IL-23R) in minor salivary glands (MSGs) of patients with primary Sjögren's syndrome (pSS). Expression of IL-17, IL-23 and receptors of IL-17/-23 was analyzed in MSGs from 25 patients with pSS, 25 patients with probable preclinical pSS, and 25 patients ...

Ranula is a cystic fluid filled cavity that caused by extravasation of the sublingual gland at floor mouth. originates in body gland, especifically Rivinus ducts and occasionally minor salivary glands mouth .There are variety treatment modalities for ranula including aspiration fluid, sclerotherapy, marsupialization, incision drainage, excision only, with or without ranula. In this article we p...

Papillary cystadenocarcinoma is an extremely rare malignant tumor of the salivary glands. Major locations of this neoplasm are the parotid gland, sublingual gland, and minor salivary glands, while occurrence in the submandibular gland is extremely rare. Magnetic resonance imaging (MRI) findings of this lesion have not been reported in the literature. Herein, we present a case of papillary cysta...

Polycystic (dysgenetic) disease of the salivary glands is a rare entity that has only recently been described in the literature. The disease is more commonly seen in females and majority of the cases have presented as bilateral parotid gland swellings. This case presenting in a 21-year-old male is the first of this unusual entity involving solely the minor salivary gland on the lower lip. This ...

OBJECTIVE To determine an appropriate focus score cutoff for childhood Sjögren syndrome (SS). METHODS Labial salivary gland tissue from specimens from children with SS and age-matched controls was retrospectively identified and reviewed by a blinded oral pathologist. RESULTS The presence of any focal sialadenitis (focus score > 0 foci/4 mm(2)) was common among childhood SS samples but prese...

We report a surgical case of primary polymorphous low-grade adenocarcinoma (PLGA) of the minor salivary gland-type of the lung. A PLGA originating from the right upper lobar bronchial inlet was successfully treated by sleeve right upper lobectomy. PLGAs are thought to be indolent tumors that are preferentially localized to the palate, and they affect the minor salivary glands almost exclusively...

BACKGROUND Malignant tumours of minor salivary glands are uncommon, representing only 2-4% of all head and neck cancers. In the larynx, minor salivary gland tumours rarely occur and constitute less than 1% of laryngeal neoplasm. Most of the minor salivary gland tumours arise in the subglottis; however, they can also occur in the supraglottis, in the false vocal cords, aryepiglottic folds and ca...

The human kallikrein 13 protein (hK13) is expressed in many normal tissues. Petraki et al have previously described presence of hK13 in salivary gland tissue, localized to duct epithelia and some acinar cells. The aim of this study was to determine whether hK13 is expressed in salivary gland tissues and salivary gland tumors (both benign and malignant), in order to compare normal with tumor tis...