Abstract Staphylococcus aureus is one of the most common pathogens in biofilm-associated chronic infections. S. living within biofilms evades host immune response and more resistant to antibiotics than planktonic bacteria. In this study, we generated with low high levels biofilm formation using rbf (regulator formation) gene performed a BioTimer assay determine minimum inhibitory concentration ...

Plant extracts and essential oils are promising new sources of non-toxic alternatives to chemicals substances. They used for their antimicrobial properties against plant diseases fungal origin, bacterial, those virus origin. This study was carried out the antifungal activity Artemisia herba-alba, Foeniculum vulgare Citrus sinensis Fusarium oxysporum f. sp. albedinis. Essential oil extracted by ...

Bacteria have acquired resistance against almost all antibiotics because of the misuse antibacterial agents and long periods treatment. Antimicrobial peptides (AMPs) are one most encouraging candidates to solve this problem, as they possess high prokaryotic selectivity, affect bacteria by a unique mode action. Novel cyclic undecapeptides (QNRNFYFNRNQ QNRNFHFNRNQ) their linear counterparts were ...

Tulathromycin is the first member of the triamilide antimicrobial drugs that has been registered in more than 30 countries. The goal of this study is to provide a potential new indication of tulathromycin for Streptococcus suis infections. We investigated the pharmacokinetic and ex vivo pharmacodynamics of tulathromycin against experimental S. suis infection in piglets. Tulathromycin demonstrat...

objective(s) the aim of this study was to investigate the presence of per-1-type esbls in drug resistant pseudomonas aeruginosa isolates. materials and methods during one-year period (2008-2009), following isolation and identification of 56 p. aeruginosa, the e-test method was performed for determination of minimal inhibitory concentration of ceftazidim. the isolates that they had mic≥16 µg/ml ...

BACKGROUND Essential oil components eugenol and carvacrol (ranging between 100 and 200 ppm for carvacrol and between 250 and 750 ppm for eugenol) were tested for antifungal activity against foodborne pathogenic fungal species Aspergillus carbonarius A1102 and Penicillium roqueforti PTFKK29 in in vitro and in situ conditions. MATERIALS AND METHODS In vitro antifungal activity of eugenol and ca...

Pharmacodynamic properties can be used to divide antibiotics into two major classes based on their mechanism of bactericidal action: (1) concentration-dependent drugs, such as aminoglycosides and fluoroquinolones, and (2) concentration-independent drugs, including the beta-lactams. Antibiotics also differ in the postantibiotic effect (PAE) that they exert. In general, concentration-dependent dr...

Background: The increasing resistance to antifungal drugs and the reduced number of available drugs led to the search for therapeutic alternatives among aromatic plants and their essential oils, empirically used by antifungal effects. OBJECTIVES: The purpose of the current study was to evaluate the antifungal activity of Trachyspermum ammi essential oil (EO) against the most frequent pathogenic...

Aromatic plants are rich in essential oils with considerable antimicrobial properties.The aim of this study was to investigate chemical composition, antimicrobial activity and antioxidant properties of Melissa officinalis and Deracocephalum moldavica essential oils (EOs). The identification of chemical constituents of the EOs was carried out using gas chromato-graphy-mass spec...