BACKGROUND Acne vulgaris is the most common disease of the skin affecting adolescents and young adults causing psychological distress. The combination of antibiotic resistance, adverse effects of topical and systemic anti acne medications and desire for high tech approaches have all led to new enthusiasm for light based acne treatment. Intense pulse light (IPL) therapy has three modes of action...

Acne is one of the most common skin diseases affecting majority of the teens and reaching its pinnacle during adulthood. In certain severe cases, it mounts to pronounced skin deformity. This appears to adversely dampen the self esteem of the affected which can eventually lead to depression and even suicides. The disease invariably diminishes in twenties but in some cases, it might even persist ...

Introduction: Acne vulgaris is the most common dermatological disorder in Treatment is essential to prevent physical and psychological scarring. Although many treatments for acne are available, effective with the emergence of antibiotic-resistant strains of Aim: The aim of this study is to evaluate the efficacy of oral azithromycin in acne by comparing its effect with the most common therapy us...

Background: Acne is a self-limiting chronic inflammatory disorder of pilosebaceous follicles seen among young adults with significant psychological and social impact. Tretinoin which was widely used for many years is being replaced gradually by newer generation agents like Tazarotene and Adapalene which unlike Tretinoin are specific for a subset of retinoic acid receptors. Objectives: To compar...

In this study we have evaluated the use of blue light (peak at 415 nm) and a mixed blue and red light (peaks at 415 and 660 nm) in the treatment of acne vulgaris. One hundred and seven patients with mild to moderate acne vulgaris were randomized into four treatment groups: blue light, mixed blue and red light, cool white light and 5% benzoyl peroxide cream. Subjects in the phototherapy groups u...

Acne vulgaris is a common skin disease and has complex pathogenesis. There no enough data related with oxidative stress in acne vulgaris. We purposed to assess total oxidant antioxidant status included 32 patients 35 healthy controls this study. Global Grading System (GAGS) scores were calculated. Serum (TOS) (TAS) levels evaluated index (OSI) was calculated by proportion of the TOS TAS. Mean G...

Acne conglobata is an uncommon and severe, inflammatory form of acne vulgaris that is characterized by interconnecting abscesses, draining sinus tracts, and severe disfigurement. We present a case of a 26-year-old female with a past medical history of mild acne that suddenly developed many papules, pustules, and fluctuant nodules on her face and back after pregnancy that was consistent with a d...

BACKGROUND Although photodynamic therapy (PDT) is widely performed for acne, little is known about its exact therapeutic mechanism. OBJECTIVE We aimed to estimate the efficacy and safety of PDT on acne and to discover its mode of action. METHODS We performed PDT on 12 patients with mild to moderate acne. The clinical efficacy was assessed by counting the acne lesions and measuring the sebum...

The fixed-dose combination adapalene 0.1%/benzoylperoxide 2.5% (A/BPO) was introduced as an acne vulgaris therapeutic in 2007. It combines anti-inflammatory, keratolytic, comedolytic, and antibacterial properties. Thus, it addresses several pathophysiological factors involved in the pathophysiology of acne. This review highlights the rationale for the use of this fixed-dose combination product,...

The management of acne vulgaris in the setting of pregnancy raises important clinical considerations regarding the efficacy and safety of acne treatments in this special patient population. Particular challenges include the absence of safety data, discrepancy in safety data between different safety rating systems, and lack of evidence-based recommendations for the treatment of acne during pregn...