This work introduces and demonstrates the concept of Lab-on-a-Printer whereby microfluidic components are integrated with inkjet dispensers. This concept allows for multi-functional microfluidic materials processing to be performed on chip and direct post-process printing of those materials enabling printing of programmable gradients and more generally structures with programmable composition. ...

We fabricate and measure a microfluidic variable optical attenuator, which consists of an optical waveguide integrated with a microfluidic channel. An opening is introduced in the upper cladding of the waveguide in order to facilitate the alignment and bonding of the microfluidic channel. By using fluids with different refractive indices, the optical output power is gradually attenuated. We obt...

An easy and cheap fabrication method for intricate polydimethylsiloxane microfluidic devices is presented. The acrylonitrile butadiene styrene scaffold-removal method uses cheap, off-the-shelf materials and equipment for the fabrication of intricate microfluidic devices. The versatility of the method is proven by the fabrication of 3D multilayer, ship-in-a-bottle, selective heating, sensing, an...

Microfluidic technologies' ability to miniaturize assays and increase experimental throughput have generated significant interest in the drug discovery and development domain. These characteristics make microfluidic systems a potentially valuable tool for many drug discovery and development applications. Here, we review the recent advances of microfluidic devices for drug discovery and developm...

Microfluidic techniques allow precise control of fluids and particles at the nanoliter scale and facilitate simultaneous manipulation and analysis of cultured cells, starting from a single cell to larger populations and to intact tissues. The use of integrated microfluidic devices has considerably advanced the fields of quantitative and systems biology. In this review, we survey the recent deve...

Microfluidic technology holds great promise for the creation of advanced cell culture models. In this review, we discuss the characterization of cell culture in microfluidic systems, describe important biochemical and physical features of the cell microenvironment, and review studies of microfluidic cell manipulation in the context of these features. Finally, we consider the integration of anal...

We report on two microfluidic elastomeric autoregulatory devices-a diode and a rectifier. They exhibit physically interesting and complex nonlinear behaviors (saturation, bias-dependent resistance, and rectification) with a Newtonian fluid. Due to their autoregulatory properties, they operate without active external control. As a result, they enable increased microfluidic device density and ove...