Background Microcystic adnexal carcinoma (MAC) is a rare skin neoplasm that has not been characterized on molecular basis. Aim To assess expression profiles of Hedgehog (HH) signalling molecules in MAC and control tumours. Methods Immunohistochemistry was performed for Sonic (SHH), Indian (IHH), Patched 1 (PTCH1) Smoothened (SMO) patient tissue (n = 26) tumour tissue, including syringoma (SyG; ...

We present the case of 80-year-old male with superficial papillary urothelial carcinoma of the urinary bladder with striking multicystic architecture with a combination of features of urothelial carcinoma with gland-like lumina, with signet-ring cell differentiation and microcystic pattern. However, the tumor shared the morphologic features of several variants of urothelial carcinoma, the most ...

CONTEXT The presence of a combined serous cystadenoma and pancreatic endocrine neoplasm is a distinct clinicopathological entity rather than the incidental concurrence of two separate entities. CASE REPORT We report the case of a 52-year-old woman admitted to our hospital who had suffered from epigastric pain, nausea and vomiting for 4 months. Imaging techniques showed an irregular mass havin...

AIMS To clarify the clinical features and the natural history of serous cystic neoplasm (SCN) of the pancreas. METHODS We retrospectively analyzed data from 30 patients affected by SCN. SCNs were classified as (1) microcystic type, (2) micro- and macrocystic type, and (3) macrocystic type according to the modified WHO classification. Eighteen patients who underwent serial radiographic imaging...

OBJECTIVE The aim of this study was to evaluate the therapeutic effects of intralesion injection of pingyangmycin in combination with triamcinolone acetonide or pingyangmycin alone on lymphatic malformations in oral and maxillofacial regions. METHODS Twenty-nine cases with lymphatic malformations in the oral and maxillofacial region were divided into experimental and control groups. Thirteen ...

Benign serous cystic tumors of the pancreas are rare and include microcystic serous adenoma, serous oligocystic adenoma (SOA), illdemarcated adenoma, and macrocystic serous cystadenoma. Microcystic serous adenoma usually present are either unilocular cyst or single lesion containing fewer cysts of more than 2 cm in diameter. It is a rare tumor which usually varies from 2–10 cm in size and at ti...

BACKGROUND A lymphangioma, also called a lymphatic malformation, is a congenital condition that frequently occurs in young children. It is classified into 3 groups depending on the size of the cysts (macrocystic, microcystic, and mixed). Spontaneous regression occurs in some cases; however, the characteristics of patients who show regression have not been studied previously. Furthermore, the ty...