The endometrium undergoes a dynamic proliferation of cells and vascular tissue under the influence ovarian steroid hormones. Implantation is an essential process in development pregnancy, where there close contact between embryo uterus, including supposition, adhesion, invasion. changes occur human endometrium, endometrial secretion changes, blood vessels, immune response, leading to uterine re...

In the present study, the effects of morphine sensitization on morphine-induced impairment of memory formation and the state-dependent retrieval of a passive avoidance task learned under morphine influence have been investigated in mice. Pre-training administration of morphine (0.5, 2.5 and 5 mg/kg) dose dependently suppressed the learning of one-trial passive avoidance task. Pre-test administr...

In the present study, the effects of morphine sensitization on morphine-induced impairment of memory formation and the state-dependent retrieval of a passive avoidance task learned under morphine influence have been investigated in mice. Pre-training administration of morphine (0.5, 2.5 and 5 mg/kg) dose dependently suppressed the learning of one-trial passive avoidance task. Pre-test administr...

Ichthyosis (ikTHeosis) uterus is a rare benign metaplastic transformation of uterine endometrium into stratified squamous epithelium. The word ichthyosis (plural ichthyoses) comes from two ancient Greek (ixtus), meaning fish and disease. epithelium parakeratotic with absent granular layer. Premalignant potential this has not been established due to the rarity occurrence. We report case 72 year ...

Introduction: Our previous study has showed that chronic administration of magnesium oxide nanoparticles (MgO NP) can reduce anxiety in adult male rat. In this study the effects of MgO NP on anxiety induced by morphine withdrawal were investigated in adult male mice. Methods: Adult male NMRI mice (weighing 27 ± 3 g) divided into groups: control, receiving intraperitoneal (i.p.) injection...

The effects of cholecystokinin (CCK) receptor antagonists on hypothermia induced by cocaine or morphine have been studied in mice. In the present work, subcutaneous (SC) injection of cocaine (50-150 mg/kg) or morphine (125-500 mg/kg) induced hypothermia in mice. Administration of CCKA receptor antagonist MK-329 (0.5-1.5 mg/kg), CCKB receptor antagonist L-365, 260 (0.5-1.5 mgl kg) and CCK r...

Background and aims: The "Uterus" or "Womb" is a part of the female reproductive tract that receives the fertilized ovum from the oviduct, provides the bed for implantation and establishes the vascular connections necessary for sustenance of the embryo throughout its development. Due to increasing rate of infertility, the reproductive organs are gaining importance. The aim of the study is to as...

Remodelling of the extracellular matrix (ECM) occurs during decidualization of the endometrium in mice. Previously we have documented the appearance of large-diameter collagen fibrils around mature decidual cells between day 5 and day 7 of pregnancy. Proteoglycans are important in the regulation of collagen fibrillogenesis, and the present study analysed four members (decorin, biglycan, lumican...

Background: Opioids may affect hypothalamic GnRH secretion and Hypothalamic-Pituitary- Gonad axis, resulting in reproductive disturbances. Current study investigates the effects of morphine on structure of ovary following superovulalion through morphologic/morphometric studies. Methods: Twelve young female NMRI mice were allocated into treatment and control groups. Treatment group received oral...

BACKGROUND AND AIM Morphine co-injection has anti-inflammatory effects on zymosan-induced peritonitis in several strains of mice except that of CBA. As peritoneal mast cells (pMCs) are much more numerous in CBA mice than in SWISS mice, therole of pMCs in morphine-modulated zymosan peritonitis is compared in CBA and SWISS males. METHODS pMCs were treated in vitro with morphine or C48/80 for co...