more toxic by intraperitoneal injection than any of the simple peroxides with which it was compared. Autoxidized methyl linoleate was less toxic than most of the simple peroxides. 5. The LD50 of autoxidized linoleic acid (0.26 ,mole of peroxide/g.) was only slightly higher than the mean increase of peroxide previously found in mice after 950r. of X-rays (0.22 lamole/g.). 6. Injected peroxides k...

N-hydroxyphthalimide (NHPI) is an organocatalyst for free-radical processes able to promote the aerobic oxidation of a wide range of organic substrates. In particular, NHPI can catalyze the hydroperoxidation of polyunsaturated fatty acids (PUFA). This property could be of interest for biological applications. This work reports the synthesis of two β-cyclodextrin derivatives (CD5 and CD6) having...

Fatty acid methyl esters (FAMEs) were obtained from vegetable oils of soybean, corn and sunflower. The current study was focused on evaluating the antifungal activity of FAMEs mainly against Paracoccidioides spp., as well as testing the interaction of these compounds with commercial antifungal drugs and also their antioxidant potential. FAMEs presented small IC50 values (1.86-9.42 μg/mL). All t...

KARAMAĆ M., BUCIŃSKI A., PEGG R. B., AMAROWICZ R. (2005): Antioxidant and antiradical activity of ferulates. Czech J. Food Sci., 23: 64–68. Antioxidant and antiradical activities of ferulates (i.e., ferulic acid, isoferulic acid, coniferyl aldehyde, and methyl ferulate) were investigated using a β-carotene-linoleate model system and a DPPH radical scavenging assay, respectively. Compounds so te...

Retinyl acetate suppressed the free radical-induced oxidation of methyl linoleate. Retinyl acetate was reacted with an alkylperoxyl radical in two solvent systems, methanol and benzene, The alkylperoxyl radical was generated by the thermal decompositien of a free radical initiator, 2 2'-azobis(2,4-dimethylyaleronitrile), at 370C. The reaction products were isolated by HPLC and their structures ...

The structural isomers formed by the homogeneous rhodium-catalyzed isomerization of several vegetable oils have been elucidated. A detailed study of the isomerization of the model compound methyl linoleate has been performed to correlate the distribution of conjugated isomers, the reaction kinetics, and the mechanism of the reaction. It has been shown that [RhCl(C8H8)2]2 is a highly efficient a...