The methanolic extract from the leaves of Salacia chinensis collected in Thailand was found to show a protective effect on D-galactosamine-induced cytotoxicity in primary cultured mouse hepatocytes. From the methanolic extract, eight new glycosides, named foliachinenosides E, F, G, H, and I, and foliasalaciosides J, K and L, were isolated together with 26 known constituents. The structures of n...

Isolated five known iridoids glycosides (Scrophuloside A, Harpagoside B, 5-hydroxyloganin, 8-O-acetylharpagide and 6-O-methyl,1-glucopyranosyl catalpol), one phenyl ethanoid glycoside (Verbascoside) and a phenyl ethanol amine (2-(4-Chlorobenzyl amino) ethanol) compound from the methanolic extract of aerial parts of Scrophularia oxysepala using by high performance liquid chromatographyare based ...

The present investigation deals with the in-vivo acute toxicity studies and in-vivo anti-inflammatory activity by Carrageenan induced rat paw edema model of methanolic extract in the stems of Cissus Vitiginea. The Literature review reveals the presence of steroids, flavonoids, triterpenoids, and glycosides in Cissus Vitiginea. Some plants belonging to Cissus genus have been reported to possess ...

BACKGROUND The present paper describes the isolation and characterization of two new aliphatic δ-lactones along with three glycerides and n-nonadecanyl cetoleate from the fruits of Coriandrum sativum L. (Apiaceae). The structures of all the isolated phytoconstituents have been established on the basis of spectral data analysis and chemical reactions. RESULTS Phytochemical investigation of the...

BACKGROUND Thevetia peruviana (Pers.) K. Schum or Cascabela peruviana (L.) Lippold (commonly known as ayoyote, codo de fraile, lucky nut, or yellow oleander), native to Mexico and Central America, is a medicinal plant used traditionally to cure diseases like ulcers, scabies, hemorrhoids and dissolve tumors. The purpose of this study was to evaluate the cytotoxic, antiproliferative and apoptotic...

Results Dose response anti HBV revealed that methanolic extract C. asiatica indicated that 2.5 mg/mL concentrations was inhibitory to 0.75 pg/mL of HBV. Aqueous and methanolic extract of C. sinensis indicated that 0.5 mg/mL and 0.25 concentrations inhibited HBV, respectively. Interestingly, EGCG indicated 1.5 pg/mL HBV was inhibited by 25μg/mL. These concentrations were well tolerated by HepG2 ...

The objective of this study was to determine antioxidant and cytotoxic efficacies of methanolic and aqueous extracts of Rheum emodi Wall. ex Meissn. rhizome. 2,2-Diphenyl-1-picrylhydrazyl (DPPH) and hydroxyl radical scavenging activities, inhibitory effect on lipid peroxidation and Fe(3+) reducing antioxidant property have been used to investigate antioxidant properties of the extracts. Cytotox...

Department of Biochemistry Federal University of Technology, Minna, Nigeria. Corresponding Author: Saidu, A.N __________________________________________________________________________________________ Abstract The phytochemical screening and hypoglycemic effect of methanolic extract of Gongronema latifolium leaf in alloxan induced diabetic rats were investigated. The methanolic extract of Gongr...

This study revealed polyphenolic content, nutritive content, antioxidant activity, and phenolic profile of methanol and aqueous extracts of Punica granatum peel extract. For this, extracts were screened for possible antioxidant activities by free radical scavenging activity (DPPH), hydrogen peroxide scavenging activity and ferric-reducing antioxidant power (FRAP) assays. The total phenolics and...

Citrus plants are known to possess beneficial biological activities for human health. In addition, ethnopharmacological application of plants is a good tool to explore their bioactivities and active compounds. This research was carried out to evaluate the phenolic and flavonoid analysis, antioxidant properties, anti inflammatory and anti cancer activity of Citrus aurantium bloom. The total phen...