The design of district metered areas (DMA) in potable water supply systems is paramount importance for utilities to properly manage their systems. Concomitant main objective, namely, deliver quality consumers, the benefits include leakage reduction and prompt reaction cases natural or malicious contamination events. Given structure a distribution network (WDN), graph theory basis DMA design, cl...

This paper proposes a model based detection and localisation method to deal with abnormal quality levels based on the chlorine measurements and chlorine sensitivity analysis in a water distribution network. A fault isolation algorithm which correlates on line the residuals (generated by comparing the available chlorine measurements with their estimations using a model) with the fault sensitivit...

Inhalation product development is an important area of activity for the pharmaceutical sector. Asthma and chronic obstructive pulmonary disease (COPD) are becoming increasingly common and there is growing recognition of the benefits of the pulmonary route for systemic drug delivery. The industry is responding by investing heavily in both formulation and device research. Inhalation delivery plat...

Continuous glucose monitors (CGMs) measure interstitial fluid (ISF) glucose, and provide information about continuous glucose fluctuations that is not otherwise captured by intermittent blood glucose testing. CGMs may benefit patients having difficulty controlling their blood sugar or during initiation or monitoring of insulin pump use. CGMs require calibration with finger-stick tests and suppl...