BACKGROUND The presence of gastric metaplasia allows helicobacter pylori to colonise the duodenum and this condition is thought to be acquired as a response to acid hypersecretion. This functional disorder, however, is present only in a subgroup of duodenal ulcer patients and, in addition, surface gastric metaplasia has been frequently found in the proximal duodenum of normal subjects and patie...

This paper presents a case of osseous metaplasia of the endometrium, a rarely encountered disease. Metaplasia is described as a change of one epithelium into another epithelium due to some triggering factor. In this case, endometrium is converted into osseous spicules. It might be followed by an abortion presenting with Infertility or chronic endometritis or metabolic disorder like hypervitamin...

Barrett esophagus is characterized by the replacement of squamous mucosa in the esophagus by specialized intestinal metaplasia. Its clinical significance lies in it being the strongest risk factor for and known precursor for esophageal adenocarcinoma. Diagnosis requires endoscopic confirmation of columnar metaplasia in the distal esophagus and histologic confirmation of specialized intestinal m...

BACKGROUND Goblet cell metaplasia that causes mucus hypersecretion and obstruction in the airway lumen could be life threatening in asthma and chronic obstructive pulmonary disease patients. Inflammatory cytokines such as IL-13 mediate the transformation of airway ciliary epithelial cells to mucin-secreting goblet cells in acute as well as chronic airway inflammatory diseases. However, no effec...

OBJECTIVES The objective of this study was to evaluate the prevalence of atrophic gastritis and intestinal metaplasia according to gender, age and Helicobacter pylori infection in a rural population in Korea. METHODS Between April 2003 and January 2007, 713 subjects (298 men and 415 women, age range: 18-85) among the 2,161 adults who participated in a population-based survey received gastroin...

High-virulence Helicobacter pylori strains and smoking increase the risk of gastric precancerous lesions. However, its association with specific types of intestinal metaplasia has been poorly studied. We aimed to quantify the association between different types of intestinal metaplasia (complete, incomplete, and mixed) and these two risk factors. Male volunteers (n = 227) underwent an upper dig...

The case of a 2.5-year-old sheep sent for diagnostic evaluation is presented. At the necropsy, mucoid degeneration coronary fat, pleural adhesions, hypostatic congestion, hemoperitoneum, reticulum, rumen, omasum, and abomasum distention were found. most significant finding was whitish, hard-to-touch appearance right atrium. atrial sample decalcified sectioning histopathology study. histology se...

Abstract Background Paneth cells are normally found in the small intestine, and when left colon, they represent cell metaplasia (PCM). This finding indicates a chronic inflammatory state is seen some patients with bowel disease (IBD). However, intestinal differentiation beyond PCM has not been reported. We report broader range of sigmoid colon IBD, including loss expression colonic marker SATB2...

Background: Phyllodes tumors (PTs) are uncommon biphasic fibroepithelial neoplasms of the breast occurring in elderly females with a peak incidence between 45 and 49 years. Depending on various histological criteria, they are subdivided into benign, borderline, and malignant forms. Metaplastic changes occur, but are quite infrequent and cystic squamous metaplasia is ve...

MMM usually presents with fatigue, weight loss, splenomegaly with or without symptoms. Anemia and various alterations of the white blood cell and/or platelet count are frequently seen at diagnosis. Thrombocytopenia-related bleeding may occur. MMM must be distinguished from myelodysplasia with fibrosis, from acute megakayoblastic leukemia and acute myelofibrosis. As the disease progresses, incre...