normal 0 false false false en-us x-none ar-sa previous studies have inspected the associations between adiponectin (adipoq) 276g/t polymorphisms and atherosclerosis, but the results are inconclusive. the aim of this study was to explore the relationship between polymorphism +276 g > t (rs1501299) in adipoq and atherosclerosis. a widespread search was directed to identify all studies on the asso...

conclusions the current meta-analysis showed an association between frequency of gg genotype of pnpla3 and the risk of development of chc in various populations throughout the world. results five hospital-based case-control studies were included in the final analysis. the overall frequency of pnpla3 gene polymorphisms was 20.4% (205/1005) in chc and 10.23% (53/518) in controls. the summary odds...

Meta-analyses synthesize multiple primary studies and identify patterns of relationships. Differences in primary study methodological quality must be addressed for meta-analysis to produce meaningful results. No single standard exists for addressing these quality variations. Quality measurement scales are fraught with development and application problems. Several strategies have been proposed t...

Recent years have seen a growing reliance on "evidence-based" guidelines or consensus statements, in which rigorous, explicit methods are used to translate the complex findings of scientific research into operational recommendations for medical care. Various factors can affect the validity of the conclusions they express, however. The purpose of this review was to compare the levels of evidence...

The current meta-analytic study examined the differential impact of maltreatment and various socioeconomic risks on attachment security and disorganization. Fifty-five studies with 4,792 children were traced, yielding 59 samples with nonmaltreated high-risk children (n = 4,336) and 10 samples with maltreated children (n = 456). We tested whether proportions of secure versus insecure (avoidant, ...

BACKGROUND Indirect treatment comparison (ITC) and mixed treatment comparisons (MTC) have been increasingly used in network meta-analyses. This simulation study comprehensively investigated statistical properties and performances of commonly used ITC and MTC methods, including simple ITC (the Bucher method), frequentist and Bayesian MTC methods. METHODS A simple network of three sets of two-a...

We review the results of a series of meta-analyses by the first author and colleagues, examining age-related differences in selective attention (Stroop-task survey and negative-priming task survey) and in divided attention (dual-task survey and task-switching survey). The four task families all lent themselves to state trace analysis, in which performance in baseline conditions was contrasted w...