PURPOSE To investigate binocular visual acuity and depth of focus when one eye forms images through a typical pupil diameter aperture (4 mm) and the other eye through a small pupil of 1.5-mm diameter. METHODS Using a recently developed adaptive optics binocular visual simulator, through focus monocular and binocular visual acuity were measured in three subjects under specially simulated visua...

Purpose To examine the topographic correlation between retinal morphology and retinal sensitivity by mesopic and scotopic fundus-controlled perimetry (FCP) in eyes with intermediate AMD. Methods Thirty-five eyes from 32 patients (mean age 70.9 years) and 29 age-matched controls prospectively underwent spectral-domain optical coherence tomography (SD-OCT) imaging. Mesopic (Goldman III, 200 ms,...

Purpose To evaluate the measurement of anisocoria in a group of ocular healthy subjects using a standardized protocol in scotopic, mesopic, and photopic lighting conditions, and determine the optimal threshold of difference in pupil diameter in determining physiologic anisocoria. Methods Right and left pupil diameters of 126 ocular healthy subjects with a mean age 30.5±7.8 years (40 males and...

This is the cover letter for our paper entitled “A Tone Reproduction Operator for All Luminance Ranges Considering Human Color Perception”. This document explains the details of the proposed method, especially, the opponent color spectral sensitivities computed during the operation of the proposed method and the wavelength discrimination curves that correspond to the adapted retinal illuminance...

PURPOSE To evaluate the effects of three increasing powers of monovision contact lenses on both objective and subjective vision in emmetropic presbyopic patients. METHODS A prospective single-center study was conducted on 50 emmetropic presbyopic patients with a mean age of 55.4 +/- 4.3 years (range, 50 to 66). Each patient wore for 1 week a +0.75 D, +1.50 D, and +2.50 D contact lens in the n...

Under low illumination conditions, such as moonlight, there simply are not enough photons present to create a high quality color image with integration times that avoid camera-shake. Consequently, conventional imagers are designed for daylight conditions and modeled on human cone vision. Here, we propose a novel sensor design that parallels the human retina and extends sensor performance to spa...

PURPOSE To determine the 1-year changes of mesopic higher order aberrations (HOAs) and contrast sensitivity (CS) after accelerated corneal cross linking (CXL) in progressive keratoconus. METHODS In this prospective case series, 70 eyes of 62 keratoconic patients underwent accelerated CXL (18 mW/cm2, 5 min). HOAs and CS were measured using the OPD Scan III and CSV-1000 CS test charts under mes...

This study investigates how rod and cone inputs are combined in the magnocellular (MC) pathway in the mesopic luminance range, when both rods and cones are active. Responses of parafoveal MC ganglion cells from macaque retina were measured as a function of temporal frequency (0.62-20 Hz) or contrast (0.05-0.55) at mesopic light levels (0.2, 2, 20, and 200 td). Stimuli were of three modulation t...

PURPOSE To theoretically and experimentally assess a new aspheric diffractive trifocal intraocular lens (IOL). SETTING Centre Spatial de Liège, Liège, Belgium. DESIGN Evaluation of diagnostic test or technology. METHODS The theoretical profile of the IOL was designed using software simulation and validated by optical calculation software tools that enabled complete theoretical characteriz...