background: acid phosphatase (acp) is suggested to be one of the virulence factors in leishmania and a correlation has been reported between leishmanial acid phosphatase (acp) activity and the severity of the disease in all types of leishmaniasis including zoonotic cutaneous leishmaniasis (zcl), which is a polymorphic disease.   objective : characterization of leishmania and its correlation wit...

We investigate noise-induced pattern formation in a model of cancer growth based on Michaelis-Menten kinetics, subject to additive and multiplicative noises. We analyse stability properties of the system and discuss the role of diffusion and noises in the system’s dynamics. We find that random dichotomous fluctuations in the immune response intensity along with Gaussian environmental noise lead...

This paper reports the covalent immobilization of penicillin G acylase from E. coli on sepabeads EC-EP, an epoxy-activated polymethacrylic carrier, and describes kinetic properties of the immobilized enzyme. The selected enzyme belongs to a class of biocatalysts whose industrial interest is due to their versatility to mediate hydrolysis of penicillins and semi-synthetic β−lactam antibiotics syn...

Typically degradation of a pesticide is a biotic process, however, there are abiotic degradation processes as well. The latter include photodegradation (that can produce a wild array of products) and various types of chemical degradation processes. Restricting degradation to the soil interior (no photodegradation component) and assuming negligible chemical degradation, pesticide degradation is ...

The Michaelis-Menten model has and continues to be one of the most widely used models in many diverse fields. In the biomedical sciences, the model continues to be ubiquitous in biochemistry, enzyme kinetics studies, nutrition science and in the pharmaceutical sciences. Despite its wide ranging applications across disciplines, design issues for this model are given short shrift. This paper focu...

We develop a uniform theory for the many-particle diffusion-control effects on the Michaelis-Menten scheme in solution, based on the Gopich-Szabo relaxation-time approximation (Gopich, I. V.; Szabo, A. J. Chem. Phys. 2002, 117, 507). We extend the many-particle simulation algorithm to the Michaelis-Menten case by utilizing the Green function previously derived for excited-state reversible gemin...

Municipal wastewater consists of a large fraction particulate organic matter. During biological treatment these particles undergo extracellular depolymerisation before products are taken up by bacteria (MW < 0.6 kDa). Particle degradation and intermediate formation dynamics is important in process analysis as the transport regime differ. This work aims to develop model for particle that incl...

A simple mathematical model of steady state  oxygen distribution subject to diffusive transport and non- linear uptake in a retinal cylinder has been developed. The approximate analytical solution to a reaction- diffusion equation are obtained by using series expansions. The computational results for the scaled variables are presented through graphs. The effect of the important parameters (1) d...

Kinetics of lipase-catalyzed esterification of hexanoic acid and ethyl alcohol using the solvent-free system, surface coated lipase from Candida rugosa, had been studied. The effect of various parameters such as reaction time, reaction temperature, reaction kinetics, water removal and feasibility of solvent-free system had been focused. Candida Rugosa lipase was more effective than other li...

We study the two-dimensional reduction of the Michaelis-Menten reaction of enzyme kinetics. First, we prove the existence and uniqueness of a slow manifold between the horizontal and vertical isoclines. Second, we determine the concavity of all solutions in the first quadrant. Third, we establish the asymptotic behaviour of all solutions near the origin, which generally is not given by a Taylor...