BACKGROUND This study aimed to evaluate the effect of methylphenidate for treating mental sequelae after traumatic brain injury (TBI). METHODS Thirty-six patients with TBI were randomly divided into the intervention group and placebo group. The participants in the intervention group received methylphenidate, while subjects in the placebo group were administered a placebo. This study was condu...

Fatigue may originate from peripheral or central causes, thus being “physical” or “cognitive” (mental) in nature. Some authors also put forward the concepts “primary” or “secondary” fatigue (DeLuca, 2005). It may be that the different dimensions of fatigue have different neurobiological and neurophysiological correlates (see also Chaudhuri and Behan, 2000; 2004). The big problem, however, is th...

This paper reviews the current literature examining the pervasive symptom of fatigue experienced in three of the most common degenerative neurological conditions: multiple sclerosis (MS), Parkinson’s disease (PD) and post-polio syndrome (PPS). The existing literature can be considered under four headings definition and prevalence, type, cause, impact of fatigue. Fatigue is a common symptom in d...

BACKGROUND AND PURPOSE Fatigue is frequent and important in the lives of Parkinson's disease (PD) patients. It is multidimensional, with physical and mental aspects. The aim of our study was to explore the impact of fatigue on quality of life (QoL) for PD patients. METHODS The sample consisted of 175 PD patients from Eastern Slovakia (52% males, mean age 68.2 +/- 9.2, mean disease duration 7....

the purpose of this research is to find the relationship between mental health and job burnout among the iranian ministry of health and medical education headquarters personnel.the population under study was all the working personnel in the headquarter of above-men-tioned organization in 2007. the sample size, based on the scientific determination of sample size, was calculated to be 387 people...

BACKGROUND Fatigue is a distressing, complex, multidimensional sensation common in individuals with chronic obstructive pulmonary disease (COPD). While fatigue negatively impacts functional performance and quality of life, there has been little study of the fatigue that affects participants in pulmonary rehabilitation programs. The purpose of this study was to examine the emotional, behavioral,...

Fatigue is one of the most disabling side effects in people with multiple sclerosis. While this fact is well known, there has been a remarkable lack of progress in determining the pathophysiological mechanisms behind fatigue and the establishment of effective treatments. The main barrier has been the lack of a unified definition of fatigue that can be objectively tested with validated experimen...