No effective drugs are currently available for the treatment of mental diseases, primarily because the underlying mechanism of mental diseases have not been adequately explored at the molecular level. However, recent studies have examined several molecular cascades whose disturbances are associated with mental diseases such as schizophrenia, bipolar disease and major depression. The most common...

In a previous paper, the question of whether diagnosis is a prerequisite of psychotherapy was discussed. On the one hand we have Thorne's statement that "it seems elemental that rational therapy cannot be planned and executed until an accurate diagnosis has been made." On the other hand, Rogers writes that "diagnostic knowledge and skill are not necessary for good therapy." Thorne bases his arg...

bipolar disorder is a mental disease that can be presented as irritable mood with affective storms, mixed symptoms of depression and mania, rapid cycles, emotional labiality and irritability during all episodes. â confirmed positive familial history of the disease is the single most robust risk factor for developing the illness. this report presents 5.5 years-old girl with the symptoms of bipol...

Patients with chronic respiratory disease commonly experience comorbid mental illness. This study aimed to explore associations between illness and health, as well determine access uptake of health treatment. Mental conditions were highly prevalent, long-standing associated worse outcomes. Active treatment psychotropic drugs was common; however, acceptance non-pharmacological interventions poor...

alzheimer's disease is the most common degenerative disease of brain. nowadays, the most common treatment being used to slow down disease progression, include donepezil , rivastigmine and galantamine, which all of them act as inhibitors of acetyl cholinesterase. general purpose of our study was to show effects of treatment with donepezil and rivastigmine, as two drugs that commonly used for tre...

Knee osteoarthritis can have negative effects on the physical and mental conditions, social and family relations, general health and positive feelings of elders. For example, severe limitation of motion and increased depression, which are results of this disease, can have negative impacts on elders. The purpose of this study was to compare the levels of depression in healthy active and inactive...

1Institute of Mental Health 2Department of Psychiatry, Singapore General Hospital Address for Correspondence: Dr Kuan Tsee Chee, Woodbridge Hospital and Institute of Mental Health, Buangkok Green Medical Park, 10 Buangkok View, Singapore 539747. Email: [email protected] Introduction In medical disease, there are physical and/or mental symptoms and generally, there is a recognised aetiol...

Research has shown that risk of chronic disease increases with age. Mental disorders and chronic disease are highly comorbid, with studies showing reciprocal causal relations. However, research focuses exclusively on combinations of, or a specific, mental illness. This study investigates the hypothesis that complete mental health is a protective factor against, while mental illness is a risk fa...