Objective Cyclophosphamide (CYC) is used in clinical practice off-label for the induction of remission childhood polyarteritis nodosa (PAN). Mycophenolate mofetil (MMF) might offer a less toxic alternative. This study was undertaken to explore relative effectiveness CYC and MMF treatment randomized controlled trial (RCT). Methods an international, open-label, Bayesian RCT investigate PAN. Eleve...

From the beginning, a primary goal of the Cyc project has been to build a large knowledge base containing a store of formalized background knowledge suitable for supporting reasoning in a variety of domains. In this paper, we will discuss the portion of Cyc technology that has been released in open source form as OpenCyc, provide examples of the content available in ResearchCyc, and discuss the...

Populating the Cyc Knowledge Base (KB) has been a manual process until very recently. However, there is currently enough knowledge in Cyc for it to be feasible to attempt to acquire additional knowledge autonomously. This paper describes a system that can collect and validate formally represented, fully-integrated knowledge from the Web or any other electronically available text corpus, about v...

Abstract Background and Aims The aim of this prospective study is to investigate the long term safety efficacy intesified B-cell depletion therapy (IBCDT) in patients with active lupus nephritis (LN), comparison a conventional immunosuppresant therapy, followed by 3 year maintenence micophenolate mofetil (MMF) regimen. Method Thirty were administered an IBCDT (4 weekly rituximab [RTX] 375 mg/m2...

Hierarchical graphs are a frequent solution for capturing symbolic data due the importance of hierarchies for defining knowledge. In these graphs, relations among elements may contain large portions of the element’s semantics. However, knowledge discovery based on analyzing the patterns of hierarchical relations is rarely used. We outline four inference based algorithms exploiting semantic prop...

In this paper we try to answer the question how cross-lingual evidence may improve matching between di erent classi cation schemas. We concentrate speci cally on the task of mapping between Wikipedia categories and Cyc terms as well as the classi cation of Wikipedia articles to the Cyc taxonomy and show how this process may be improved by consuming the evidence that is available in di erent edi...

In this study we introduce a simple program for cyclic current–voltage (I–V) measurements bipolar and unipolar resistive switching devices. This (Cyclic I-V, CYC-IV) was developed under the Keysight VEE Pro (Visual Engineering Environment Program) software has graphical interface. CYC-IV programming B2912 Precision Source/Measure Unit (SMU) I-V measurement of devices in sweep mode. can be used ...

We present an approach for learning part-of-speech distinctions by induction over the lexicon of the Cyc knowledge base. This produces good results (74.6%) using a decision tree that incorporates both semantic features and syntactic features. Accurate results (90.5%) are achieved for the special case of deciding whether lexical mappings should use count noun or mass noun headwords. Comparable r...

chronic kidney disease is one of the most common complication of systemic lupus erythematosus, which if untreated can lead to  the end-stage renal disease (esrd). early diagnosis and adequate treatment of lupus nephritis (ln) is critical to prevent the chronic kidney disease incidence and to reduce the development of esrd. the treatment of ln has changed significantly over the past decade. in p...