The nucleic acid double strand helix is now known to have several structural forms that are themselves rather variable or changeable in response to environmental conditions such as ionic strength, temperature, and the presence of a wide variety of solutes in the solutions in which the solvent is almost always water. A common chemistry among all of these helical forms is the reaction that separa...

The application range of existing real scale mobile thermal storage units with phase change materials (PCM) is restricted by the low phase change temperature of 58 ∘ C for sodium acetate trihydrate, which is a commonly used storage material. Therefore, only low temperature heat sinks like swimming pools or greenhouses can be supplied. With increasing phase change temperatures, more applications...

Fibroblasts from many patients with osteogenesis imperfecta (OI) synthesize and secrete Type I collagen which is both overmodified and exhibits a decreased thermal denaturation temperature. We have examined the relationship between overmodification and decreased melting temperature in several favorable OI mutants by selectively inhibiting lysyl hydroxylase activity with the drug Minoxidil and c...

The accurate computational prediction of transcription start sites (TSS) in vertebrate genomes is a difficult problem. The physicochemical properties of DNA can be computed in various ways and a many combinations of DNA features have been tested in the past for use as predictors of transcription. We looked in detail at melting temperature, which measures the temperature, at which two strands of...

A constant-temperature, constant-density molecular-dynamics method is utilized to study the bondorientational structure and behavior in Kr-gr for the solid, fluid, and melting transition regimes at monolayer completion (r51). Several bond-orientational order parameters are introduced to help monitor the system’s symmetry behavior, both with respect to the substrate as well as intrinsic. The fir...

of all the atoms across the cluster. For an icosahedral isomer those two steps are found to be much closer in temperature (at ≈ 240 K and 270 K, respectively). For the case of Na92, the icosahedral isomer again melts in two well defined steps, surface melting at ≈ 130 K and homogeneous melting at ≈ 240 K, whereas an amorphous isomer shows an extremely broad, featureless melting transition. In t...

The temperature induced melting transition of a self-complementary DNA strand covalently attached at the 5' end to the surface of a gold interdigitated microelectrode (GIME) was monitored in a novel, label-free, manner. The structural state of the hairpin was assessed by measuring four different electronic properties of the GIME (capacitance, impedance, dissipation factor and phase angle) as a ...

The connection of twelve peripheral and divergent dodecyloxy chains to a central tridentate aromatic binding unit provides the dodecacatenar ligand L11, for which room-temperature mesomorphism is detected. An enthalpically unbalanced large melting entropy (DeltaSmL11=226 J mol(-1) K(-1)) results from the programmed microsegregation induced in the crystalline phase, a phenomenon which is maintai...

We use molecular dynamics simulations to study the influence of an ambient atmosphere on the melting process in the icosahedral palladium clusters Pdl3, Pd55 and Pd147. Novel methods to capture the character of melting in finite systems are presented. The signature of melting in clusters heated by inert carrier gas collisions closely resembles that in systems heated in a Nos6-Hoover thermostat....

The effect of microwave irradiation on DNA/DNA hybridization has been studied under controlled power and temperature conditions. It was discovered that microwave irradiation led to the melting of double-stranded deoxyoligonucleotides well below their thermal melting temperature and independent of the length of the deoxyoligonucleotides. These observations indicate a specific interaction of micr...