TO THE EDITOR: I read with interest the continuing education article by Uren et al. (1) stating that clinical prediction of lymphatic drainage from the skin is not possible and that the old clinical guidelines based on Sappey’s lines therefore should be abandoned. To the best of my knowledge, my former group at the Hospital of the Frankfurt Goethe University was the first ever to standardize sc...

The worldwide incidence of malignant melanoma is increasing at an alarming rate. The importance of diagnosing nodal metastatic disease has impacted significantly on the accurate staging and stratification of melanoma patients. As a minimally invasive procedure with low morbidity, sentinel lymph node mapping allows for a detailed histopathologic evaluation involving multiple sections, H&E staini...

TO THE EDITOR: I read with interest the continuing education article by Uren et al. (1) stating that clinical prediction of lymphatic drainage from the skin is not possible and that the old clinical guidelines based on Sappey’s lines therefore should be abandoned. To the best of my knowledge, my former group at the Hospital of the Frankfurt Goethe University was the first ever to standardize sc...

1 This paper introduces the development of a dynamic parallel algorithm for conducting 2 hydrological model simulations. This new algorithm consists of a river network 3 decomposition method and an enhanced master-slave paradigm. The decomposition 4 method is used to divide a basin river network into a large number of subbasins, and the 5 enhanced master-slave paradigm is adopted to realize the...

Blastomyces dermatitidis and Blastomyces gilchristii are dimorphic fungal pathogens that cause serious pulmonary and systemic infections in humans. Although their natural habitat is in the environment, little is known about their specific ecologic niche(s). Here, we analyzed 25 microsatellite loci from 169 strains collected from various regions throughout their known endemic range in North Amer...

Quantifying the moisture history of the Amazon Basin is essential for understanding the cause of rain forest diversity and its potential as a methane source. We reconstructed the Amazon River outflow history for the past 14,000 years to provide a moisture budget for the river drainage basin. The oxygen isotopic composition of planktonic foraminifera recovered from a marine sediment core in a re...

Background. Being predictive of the entire nodal bed, sentinel lymph node biopsy (SLNB) is invaluable in the surgical management of melanoma. Although the concept is simple, sentinel lymph node (SLN) identification and removal can be technically challenging. Methods. A total of 102 consecutive patients have undergone SLNB in the Division of Plastic and Reconstructive Surgery of Soroka Universit...

In-transit melanoma is a unique pattern of recurrence that occurs in up to ten percent of pa‐ tients with melanoma. In-transit disease denotes multifocal tumor deposits occurring be‐ tween the site of the primary lesion and its regional draining lymph node basin [1, 2]. It is an independent adverse prognostic factor and is frequently associated with distant metastasis. This pattern of recurrenc...

the land-locked country of afghanistan has a restricted but relatively diverse ichthyofauna comprising 85 species in 10 families. the fauna is dominated by cyprinidae (50 species) and other ostariophysans (28 species). eight species are endemics to afghanistan within its political boundaries. there are three principal drainage basins: the endorheic amu darya draining to the aral sea with 29 spe...

Kabani river is a 7 order stream with a basin area of 1647 km. There are 4 sixth order and11 fifth order sub-basins. This analysis is mainly confined to 11 fifth order sub basins. Morphometric indices like stream ordering, bifurcation ratio, stream length, drainage density, stream frequency, form factor, elongation ratio, circularity ratio, constant of channel maintenance, asymmetry factor, sin...