INTRODUCTION Phenylketonuria (PKU) is an autosomal recessive disorder characterized by a deficiency in phenylalanine (Phe) hydroxylase activity. Early diagnosis and continuous treatment with a low Phe diet prevents severe neurological and cognitive impairment. AIMS 1. Analyze how treatment adherence evolves through infancy, childhood, and early adolescence in individuals with PKU. 2. Identify...

Background: Given that Hodgkin’s lymphoma (HL) accounts for 5%–6% of pediatric malignancies, we investigated the clinical characteristics and survival of pediatric patients with HL in our center. Materials and methods: In this cross sectional and retrospective study, the medical charts of all patients under the age of 18 diagnosed with HL from 2006 to 2016 at Shahid Sadoughi Hospital Yazd, Ira...

BACKGROUND The aim of this study was to test the hypothesis that there is concomitant peripheral nerve involvement in patients suffering from neurodegenerative disorders by correlating motor and peripheral nerve involvement in Parkinson's disease. METHODS AND RESULTS A total of 23 patients suffering from Parkinson's disease diagnosed strictly according to the UKPDBB criteria were examined. Th...

ptk (phototherapeutic keratectomy) is the use of laser in corneal diseases. we can replace ptk for many other invasive procedures. the objective of this study is the assessment of this procedure in several cases in our practice. this investigation was a retrospective study, which was conducted based on comparison of 11 eyes with corneal eschars, induced by recurrent corneal erosions, pterygium ...