This paper summarizes characteristics of major depressive disorder (MDD) in the Oregon Adolescent Depression Project, using data from 816 participants (56% female; 89% White). Contrasting four developmental periods (Childhood [5-12.9], Adolescence [13-17.9], Emerging Adulthood [18-23.9], Adulthood [24-30]), we examine MDD incidence/recurrence, gender, comorbidity, duration, and suicide attempts...

The current study examined selective attention toward emotional images as a risk factor for major depressive disorder (MDD). Using multiple indices of attention in a dot-probe task (i.e., reaction time [RT] and eye-tracking-based measures) in a retrospective, high-risk design, we found that women with remitted MDD, compared to controls, exhibited greater selective attention toward angry faces a...

The current study examined selective attention toward emotional images as a risk factor for major depressive disorder (MDD). Using multiple indices of attention in a dot-probe task (i.e., reaction time [RT] and eye-tracking-based measures) in a retrospective, high-risk design, we found that women with remitted MDD, compared with controls, exhibited greater selective attention toward angry faces...

BACKGROUND The economic burden of depression in the United States--including major depressive disorder (MDD), bipolar disorder, and dysthymia--was estimated at $83.1 billion in 2000. We update these findings using recent data, focusing on MDD alone and accounting for comorbid physical and psychiatric disorders. METHOD Using national survey (DSM-IV criteria) and administrative claims data (ICD...

The aim of this study was to assess eventual differences in serum cholesterol, low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), triglycerides, LDL-C/HDL-C ratio between veterans with combat-related post-traumatic stress disorder (PTSD) only or comorbid with major depressive disorder (MDD), veterans with combat experiences with MDD, and healthy control g...

Borderline personality disorder (BPD) and major depressive disorder (MDD) are both associated with abnormalities in the regulation of emotion, with BPD being highly comorbid with MDD. Disorder-specific dysfunctions in BPD, however, have hardly been addressed, hence the lack of knowledge pertaining to the specificity of emotion processing deficits and their commonality with MDD. 24 healthy compa...

BACKGROUND Major depressive disorder (MDD) is a common mental disorder worldwide, but now there is a lack of clinically effective assessment and management of MDD. In this study, we used technetium-99 m ethylcysteinate dimer ([99mTc]ECD) SPECT/CT to characterize the regional cerebral blood flow (rCBF) status of MDD patients, and to explore an objective image assessment model of MDD which is non...

Major depression disorder (MDD) is a complex neuropsychiatric disorder and an increasing number of genetic risk variants are being identified. Investigation of their influence in the general population requires accurate and efficient assessment of depressive symptoms. Here, clinical interviews conducted by clinicians are the gold standard. We investigated whether valid and reliable clinical phe...

To help bridge the gap between Information system (IS) analysts and stakeholders, a Model-Driven Development (MDD) approach is proposed. A MDD approach uses models as primary development artifacts. Models increase the abstraction level of IS development and help to improve migration between various development phases. A MDD approach provides considerable benefits in the IS development domain, n...

Background: Although the relationship between sleep and depression has been studied over the past two decades, findings are inconsistent across the literature. The present study evaluated differences in sleep macroarchitecture between adults with major depressive disorder (MDD) and healthy controls, paying particular attention to sex differences. Method: Sleep macroarchitecture was investigated...