INTRODUCTION Limited data exist on the outcome of Dandy-Walker malformation (DWM), Dandy-Walker variant (DWV) and mega-cisterna magna (MCM). We report the first population-based study of posterior fossa anomalies from the northern region of England. METHODS Cases were identified from the Northern Congenital Abnormality Survey (NorCAS) and regional Fetal Medicine Unit databases for the period ...

This paper describes the system packaging of the processor cage for the IBM eServer z900. This server contains the world’s most complex multichip module (MCM), with a wiring length of 1 km and a maximum power of 1300 W on a glass-ceramic substrate. The z900 MCM contains 35 chips comprising the heart of the central electronic complex (CEC) of this server. This MCM was implemented using two diffe...

When individuals learn facts (e.g., foreign language vocabulary) over multiple study sessions, the temporal spacing of study has a significant impact on memory retention. Behavioral experiments have shown a nonmonotonic relationship between spacing and retention: short or long intervals between study sessions yield lower cued-recall accuracy than intermediate intervals. Appropriate spacing of s...

s for Invited Talks 8 Workshop on Monte Carlo for Financial Mathematics 12 Workshop on Monte Carlo for Computational Biology 15 Abstracts for Talks 18 Welcome to MCM 2007s for Talks 18 Welcome to MCM 2007 On behalf of the programme committee and the local organising committee, it is my pleasure to welcome you to the sixth International Association for Mathematics and Computers in Simulation sem...

This study aimed to assess the effect of intracellular prolactin (ICPRL) and hyperprolactinemia on cell replication, using an immunohistochemical (IHC) technique for Ki-67 and Mcm-2, and angiogenesis, using IHC for endoglin CD-105, in central nervous system (CNS) tumors. This cross-sectional study included 79 cases of surgically excised primary CNS tumors of neuroepithelial origin (41.8% of all...

BACKGROUND The origin recognition complex (ORC) and the minichromosome maintenance (MCM) protein complex were initially discovered in yeast and shown to be essential for DNA replication. Homologues of ORC and MCM proteins exist in higher eukaryotes, including Xenopus. The Xenopus MCM proteins and the Xenopus homologues of Saccharomyces cerevisiae Orc 1p and Orc2p (XOrc1 and XOrc2) have recently...

The MCM (minichromosome maintenance) proteins of archaea are widely believed to be the replicative DNA helicase of these organisms. Most archaea possess a single MCM orthologue that forms homo-multimeric assemblies with a single hexamer believed to be the active form. In the present study we characterize the roles of highly conserved residues in the ATPase domain of the MCM of the hyperthermoph...

The MCM (minichromosome maintenance) complex is a helicase which is essential for DNA replication. Recent results suggest that the MCM helicase is important for replication fork integrity, and may function as a target of the replication checkpoint. Interactions between MCM proteins, checkpoint kinases, and repair and recovery proteins suggest that MCMs are proximal effectors of replication fork...

Manganese (?) complex with 2, 2? bipyridine, 1, 1? dioxide (bpdo) ligand was immobilized within nanoreactors of MCM-41. The immobilized complex was characterized by powder x-ray diffraction (XRD), nitrogen adsorption desorption, and FTIR. The pore volume, surface area and pore diameter of MCM-41 decreased after immobilization of Mn complex. Three bands observed at 1250, 1220 cm?1 and 757 cm?1 a...

Every year, the Consortium for Mathematics and its Applications (C C C OMA OMA OMA P P P) sponsors the Mathematical Contest in Modeling (MCM), an international contest for undergraduates. We will discuss our strategy for developing models, writing the paper, the contest timeline, and team dynamics. 1 What is the MCM? In the MCM, three-person teams are given 96 hours to develop mathematical mode...