نتایج جستجو برای: mbl2

تعداد نتایج: 273  

Journal: :American journal of physiology. Endocrinology and metabolism 2012
Maryam Rakhshandehroo Rinke Stienstra Nicole J de Wit Marjolijn C E Bragt Martin Haluzik Ronald P Mensink Michael Müller Sander Kersten

The peroxisome proliferator activated receptor-α (PPARα) is a major transcriptional regulator of lipid metabolism in liver and represents the molecular target for hypolipidemic fibrate drugs. Effects of PPARα on lipid metabolism are partially mediated by circulating proteins such as FGF21 and ANGPTL4. The present study was undertaken to screen for and identify circulating proteins produced by h...

2011
Pavel Rossner Nana Tabashidze Miroslav Dostal Zuzana Novakova Irena Chvatalova Milada Spatova Radim J. Sram

BACKGROUND Oxidative damage to placental DNA can result in negative pregnancy outcomes, including intrauterine growth restriction (IUGR) and low birth weight (LBW). OBJECTIVE We investigated associations between the levels of 8-oxo-7,8-dihydro-2´-deoxyguanosine (8-oxodG), a marker of oxidative DNA damage, in placental DNA, exposure to air pollutants during pregnancy, genetic polymorphisms in ...

2012
Laszlo Denes Laszlo Entz Veronika Jancsik

The vascular disease involves imbalanced function of the blood vessels. Risk factors playing a role in development of impaired vessel functions will be briefly discussed. In ischemia/reperfusion (I/R), ischemic hypoxia is one of the cardinal risk factors of restenosis. Various insults are shown to initiate the phenotype switch of VSMCs. The pathological process, leading to activated inflammator...

Journal: :Molecules 2017
Miao Li Qin Liu Yajuan Cui Dong Li Hexiang Wang Tzi Bun Ng

A 17.5-kDa trypsin inhibitor was purified from Phaseolus vulgaris cv. "gold bean" with an isolation protocol including ion exchange chromatography on DEAE-cellulose (Diethylaminoethyl-cellulose), affinity chromatography on Affi-gel blue gel, ion exchange chromatography on SP-sepharose (Sulfopropyl-sepharose), and gel filtration by FPLC (Fast protein liquid chromatography) on Superdex 75. It dos...

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