The limbic thalamus, specifically the anterior thalamic nuclei (ATN), contains brain signals including that of head direction cells, which fire as a function of an animal's directional orientation in an environment. Recent work has suggested that this directional orientation information stemming from the ATN contributes to the generation of hippocampal and parahippocampal spatial representation...

Mouse models have been indispensable for elucidating normal and pathological processes that influence learning and memory. A widely used method for assessing these cognitive processes in mice is the Morris water maze, a classic test for examining spatial learning and memory. However, Morris water maze studies with mice have principally been performed using adult animals, which preclude studies ...

There is a wide range in the reported photon tenth value distance (TVD) in the maze of high-energy linear accelerator vaults. In order to gain insight into the appropriate use of the TVD value during door design, we performed measurements of the photon dose in the maze of four vaults. In addition, our study represents the first to describe a scenario where an inner borated polyethylene (BPE) do...

Cuda, Marissa, "Will the exploratory behavior of lobsters decrease as they become familiar with their environment?" (2013). Honors Theses. Paper 120. Abstract Previous studies have shown that most lobsters have a home range in which they reside on a daily basis. The tendency for lobsters to reside in a particular area suggests that they have the ability to learn the characteristics of an area u...

The present study examined sex differences in object memory by using 2-dimensional object arrays and in spatial memory by using a computerized virtual 12-arm radial maze. Virtual T-maze and water maze tasks were also used to examine sex differences in the use of spatial and nonspatial strategies during navigation. Women significantly outperformed men in recalling the locations and identities of...

The search for alternative epicardial energy sources in the treatment of nonvalvular atrial fibrillation (AF) is a relatively new aspect of the evolving spectrum of Maze operations. We tested the hypothesis that epicardial microwave ablation produces identical results to those of the standard cryosurgical Maze. Fourteen consecutive patients with chronic AF underwent on-pump epicardial Maze proc...

The 14-unit T-maze has proven to be a valuable tool for investigating age-associated memory impairment (AAMI). While another task widely used to evaluate AAMI, the water maze, is primarily used to evaluate allocentric hippocampal-dependent spatial memory, the 14-unit T-maze can assess egocentric procedural memory. Although several brain structures, e.g. hippocampus, parietal cortex, have been i...

Toxin-antitoxin (TA) modules are pairs of genes essential for bacterial regulation upon environmental stresses. The mazEF module encodes the MazF toxin and its cognate MazE antitoxin. The highly dynamic MazE possesses an N-terminal DNA binding domain through which it can negatively regulate its own promoter. Despite being one of the first TA systems studied, transcriptional regulation of Escher...

A single 5 min exposure to the elevated plus-maze test of anxiety renders animals insensitive to the anxiolytic effects of the benzodiazepines in this test. The purpose of the present experiments was to explore whether this phenomenon resulted from a change in the functional state of benzodiazepine receptors in the dorsal raphe nucleus. The benzodiazepine receptor agonist midazolam (0.5, 1, and...

A concrete room with a single-legged maze was constructed in order to simulate a medical accelerator room. Gamma and neutron measurements were performed along the maze with a) a 252 Cf source and b) a tungstenmoderated Cf source placed inside the room. The measurements were repeated after placing an inner borated polyethylene door of varying thickness (2.54 -10.16 cm) at 2 different locations. ...