The problem is the vaccination of a large number people in short time period, using minimum space and resources. tradeoff that this resources must guarantee good service for patients, represented by spent system queue. goal to develop digital twin which integrates physical virtual systems allows real-time mapping patient flow create sustainable dynamic center. Firstly, reach goal, discrete-even...

INTRODUCTION The substantial morbidity and mortality associated with recent cholera outbreaks in Haiti and Zimbabwe, as well as with cholera endemicity in countries throughout Asia and Africa, make a compelling case for supplementary cholera control measures in addition to existing interventions. Clinical trials conducted in Kolkata, India, have led to World Health Organization (WHO)-prequalifi...

In the discussion about policies and strategies for rabies prevention in developing countries, intervention costs arise as a major issue. We organized two pilot mass vaccination campaigns for dogs against rabies under equal conditions in N’Djaména, Chad. The first one was free of charge for the dog owners; the second one, four years later, assessed willingness to pay. 3000 dogs were vaccinated ...

INTRODUCTION Rabies is one of the major public health problems mostly affecting developing countries in Africa and Asia where 99.9% of all rabies related human deaths are recorded each year. In Democratic Republic of Congo, repeated outbreaks have been reported. Despite this, there is little reliable epidemiological data about rabies in the country for the development of effective control strat...

BACKGROUND From 2006 to 2010, France experienced two bluetongue epidemics caused by serotype 1 (BTV-1) and 8 (BTV-8) which were controlled by mass vaccination campaigns. After five years without any detected cases, a sick ram was confirmed in August 2015 to be infected by a BTV-8 strain almost identical to that circulating during the previous outbreak. By then, part of the French cattle populat...

Although industrialized countries have been able to contain recent outbreaks of zoonotic diseases, many resource-limited and transitioning countries have not been able to react adequately. The key for controlling zoonoses such as rabies, echinococcosis, and brucellosis is to focus on the animal reservoir. In this respect, ministries of health question whether the public health sector really ben...

BACKGROUND AND PURPOSE Prior to 2004, the mass immunization program in Taiwan did not include varicella vaccine; however, parents could have their children vaccinated by the self-payment option. METHODS In April 2002, we distributed 1271 questionnaires to the caregivers of children aged 1 to 6 years in Taoyuan county, Taiwan, to survey the status of vaccination rate against varicella, parenta...

Vaccines are arguably the most important means of pandemic influenza mitigation. However, as during the 2009 H1N1 pandemic, mass immunization with an effective vaccine may not begin until a pandemic is well underway. In the U.S., state-level public health agencies are responsible for quickly and fairly allocating vaccines as they become available to populations prioritized to receive vaccines. ...

BACKGROUND Brazil conducted mass rubella vaccination campaigns to meet disease elimination goals by 2010. An analysis of rubella vaccination opportunities was conducted to target population groups with concentrations of unvaccinated individuals. METHODS Rubella vaccination strategies for all 27 states were reviewed between 1992 and 2006. Yearly vaccination coverage was calculated by dividing ...

BACKGROUND The epidemiological importance of varicella and zoster and the availability of an efficacious and safe vaccine have led to an important international debate regarding the suitability of mass vaccination. The objective of the study was to describe the epidemiology of varicella and zoster in Italy and to determine whether there have been changes with respect to observations provided by...