The anti-inflammatory, antioxidant, and antimicrobial properties of artemisinin derived from water, methanol, ethanol, or acetone extracts of Artemisia annua L. were evaluated. All 4 artemisinin-containing extracts had anti-inflammatory effects. Of these, the acetone extract had the greatest inhibitory effect on lipopolysaccharide-induced nitric oxide (NO), prostaglandin E2 (PGE2), and proinfla...

The aromatic compounds of Artemisia annua were extracted by supercritical carbon dioxide. Supercritical carbon dioxide extraction of volatile flavor compounds from Artemisia annua was performed at pressure 150bar and temperature 40oC. The flow rate of CO2 was 20 g/min and the flow rate of ethanol as an entrainer was 5% of CO2 used. The extraction time was 1 h. The trapped sample by cold trap 1 ...

An efficient in vitro propagation system for an elite clone EC-353508 of Artemisia annua L., an important antimalarial drug plant has been developed. The best organogenic response, including adventitious multiple shoots and their elongation, was obtained when nodal explants were cultured on MS medium supplemented with 10μM 2-isopentenyl adenine (2iP). An average of 17.7±0.88 shoots with an aver...

The study was aimed to assess the molluscicidal and cercaricidal potential of Artemisia annua leaves under laboratory conditions. The LC50 values of different crude extracts were tested for their molluscicidal activity against immature (Group I), young mature (Group II) and adult (group III) stages of Indoplanorbis exustus using Probit analysis. Snail size and different extracts of Artemisia an...

The composition of the essential oil obtained from the dried flowering aerial parts of Artemisia annua L. (Compositae) was analysed by GC and GC/MS. Thirty-two components were identified in the essential oil of A. annua L. with campher (48.00%), 1,8-cineole (9.39%), camphene (6.98%) and spathulenol (4.89%) as major components. The essential oil was evaluated for antibacterial and antifungal act...

Glandular secreting trichomes (GSTs) are called biofactories because they are active in synthesizing, storing and secreting various types of plant secondary metabolites. As the most effective drug against malaria, artemisinin, a sesquiterpene lactone is derived from GSTs of Artemisia annua. However, low artemisinin content (0.001%~1.54% of dry weight) has hindered its wide application. We inves...

Front Cover/Cover Picture. Artemisia annua L. is an annual herb of Asteraceae family, one the famous traditional Chinese medicines, commonly known as “Qing Hao”. However, in Chongming District Shanghai, it called “Ku Cao” and has been used for women's post-natal rehabilitation a long time. In this study, five new monoterpene glycosides (1–5) two sesquiterpenoid (6 7) were isolated from water ex...

Background & Aims: In most cases, drugs used for the treatment of cancer are not effective or have unpleasant side-effects. This has forced scientists to find more effective drugs with less toxicity. Artemisia is an important medicinal plant in the world and anti-tumoral activity of some Artemisia species has been reported. This study was designed for evaluation of anti-tumoral effect of methan...

artemisia annua is an annual herb native to asia most probably china produce one of the most important sesquiterpene namely artemisinin which has antimalarial and anticancer activity. three transcription factors belonging to wrky family, two transcription factors belonging to myb family and two enzymes dbr2 and opr3 were isolated from a.  annua leaves and first inserted into pjet1.2 vector then...

Nowadays, cattle breeding is a major economic issue throughout the world. However, gastrointestinal nematode parasitism remains sanitary threat on global scale, affecting animal health, farm productivity and well-being of farmers. Until recently, chemical anthelmintics occupied prominent place in fight against these parasites. But some them have developed resistance to antiparasitic drugs. The ...