Executive Summary This brief paper discusses the strengths of the patent system and its weaknesses in terms of creating incentives for innovation. It considers how Advanced Market Commitments (AMCs) may supplement the patent system, and introduces a Comprehensive Advance Market Commitment (CAMC) proposal. It shows how both AMCs and a CAMC could increase incentives for R&D into diseases of the p...

It is widely believed that the resilience of the stock market and its ability to accurately set prices are affected by credit conditions in the economy. A scarcity of deployable capital may cause market-makers to become financially constrained, leading to a breakdown in intermediation. This paper describes another channel by which the supply of available capital affects secondary market liquidi...

We show that the proportional response algorithm for computing an economic equilibrium in a Fisher market model can be interpreted as iteratively approximating the economy by one with Cobb-Douglas utilities, for which a closed-form equilibrium can be obtained. We also extend the method to allow elasticities of substitution at most one.

This thesis consists of two studies on financial market imperfections. The first study (Chapters 2 and 3) investigates illiquidity, which is a reflection of different imperfections, and its pricing implications in the corporate bond market. The second study (Chapter 4) evaluates the impact of a short-sale ban, which is a form of financial constraints, on the equity and derivatives markets. In C...

statement of the problem many diseases to be treated by dentists require drug therapy. lack of paying enough attention to principles of drug prescription can lead to problems such as unsuccessful treatment. on the other hand, the most important way to prevent such problems is paying enough attention to prescription of drugs materials and methods in this descriptive study, 260 prescriptions rand...

introduction the umbilical cord anomalies directly effect on the life quality of the fetus. it can lead to fetal death or many problems during pregnancy and delivery. early detection of these abnormalities is of particular importance. case presentation we report a case of thin cord syndrome (tcs) in a 30-year-old pregnant woman with suprapubic pain. after termination of pregnancy, histopatholog...

tooth fusion is a developmental anomaly characterized by the :union: between the dentin and/or enamel of at least two separately developing teeth. the fusion of posterior teeth is an uncommon occurrence. in this article, we report a rare case of unilateral fusion of a mandibular second molar with a paramolar. carious exposure mandated endodontic treatment. the unusual morphology and complex roo...

trauma to primary teeth can lead to devastating sequels in development of permanent successors. the disturbance may range from enamel hypoplasia and/or hypo-calcification to arrest of dental bud development. crown dilaceration of permanent teeth is one of the consequences of trauma to deciduous teeth mainly due to intrusion or avulsion. this report presents a mandibular central incisor with dil...

background: it has been well documented that left ventricular hypertrophy (lvh) is an independent factor for cardiac death in children. the epidemiologic information reveals that there is a very high prevalence of lvh in children with chronic renal failure (crf). the purpose of this study was to evaluate the existence of left ventricular hypertrophy, its severity and other cardiac abnormalities...

results loss of consciousness (gcs drop or amnesia) was markedly associated with abnormal brain ct scan (p < 0.05). interestingly, we found 7 patients with normal clinical examination but significant abnormal brain ct scan. conclusions according to the results of our study, we recommend that all patients with minor head trauma underwent brain ct scan in order not to miss any life-threatening he...