Biomedical Engineering, Cornell University, Ithaca New York, USA Biological Statistics and Computational Biology, Cornell University, Ithaca New York, USA Clinical Sciences, Cornell University, Ithaca New York, USA Electrical and Computer Engineering, Cornell University, Ithaca New York, USA (The institution address is redundant for these affiliations because the fill-in-the-box format of the o...

An emerging research area in computational biology and biotechnology is devoted to mathematical modeling and prediction of gene-expression patterns; it nowadays requests mathematics to deeply understand its foundations. This article surveys data mining and machine learning methods for an analysis of complex systems in computational biology. It mathematically deepens recent advances in modeling ...

1 Department of Computer Science, Graduate School of Science and Engineering, Waseda University, 3-4-1 Okubo, Shinjuku-ku, Tokyo 169-8555, Japan 2 Computational Biology Research Center (CBRC), National Institute of Advanced Industrial Science and Technology (AIST), 2-43 Aomi, Koto-ku, Tokyo 135-0064, Japan 3 Department of Intelligence Science and Technology, Graduate School of Informatics, Kyot...

Title (88 chars < 120): Punctuated evolution and transitional hybrid network in an 1 ancestral cell cycle of fungi 2 3 Authors: Edgar M. Medina, Jonathan J. Turner, Raluca Gordân, Jan M. 4 Skotheim, and Nicolas E. Buchler 5 6 1 Department of Biology, Duke University, Durham, NC, 27708, USA 7 2 Center for Genomic and Computational Biology, Duke University, Durham, NC, 8 27708, USA 9 3 Department...

The mainstream application of massively parallel, high-throughput assays in biomedical research has created a demand for scientists educated in Computational Biology and Bioinformatics (CBB). In response, formalized graduate programs have rapidly evolved over the past decade. Concurrently, there is increasing need for clinicians trained to oversee the responsible translation of CBB research int...

In case a. we mentioned the lemma of Neyman & Pearson, and using log ratio statistics. In this case we have to estimate which of the two suggested hypotheses is true (which one is more likely). In case b. we have one hypothesis H0 and we have to estimate if it is true or not. In science, usually the null hypothesis H0 says the dull regular conception that everyone goes by, and the scientist wis...

1 Genomic Medicine Department, MD Anderson Cancer Center, Houston, TX 77054. USA 2 Wellcome Trust Sanger Institute, Hinxton CB10 1SA, Cambridge, UK 3 Division of Computational Biology, The Jackson Laboratory for Genomic Medicine, Farmington, CT 06031, USA 4 Departments of Medical Oncology and Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02115, USA, and Broad Institute, Cambridge, MA...

1 Biological and Environmental Science & Engineering Division (BESE), Water Desalination and Reuse Center (WDRC), King Abdullah University of Science and Technology (KAUST), Thuwal 23955-6900, Saudi Arabia; [email protected] 2 CosmosID, Inc., Rockville, MD 20850, USA; [email protected] (N.A.H.); [email protected] (P.S.); [email protected] (C.H.); rita.colw...

D. W. Th ieltges ([email protected]), Dept of Marine Ecology, NIOZ Royal Netherlands Inst. for Sea Research, PO Box 59, NL-1790 AB Den Burg Texel, the Netherlands. – P.-A. Amundsen, Dept of Arctic and Marine Biology, Faculty of Biosciences, Fisheries and Economics, Univ. of Troms ø , NO-9037 Troms ø , Norway. – R. F. Hechinger, Marine Science Inst. and Dept of Ecology, Evolution and Marin...

1 Marine Science and Technology, Faculty of Fisheries and Marine Sciences, Bogor Agricultural University (IPB), Bogor, Indonesia, 2 Center for Coastal and Marine Resource Studies, Bogor Agricultural University (IPB), Bogor, Indonesia, 3 Biotechnology and Molecular Genetics, University of Bremen, Bremen, Germany, 4 Marine Biology, Ecology and Biodiversity, Vrije Universiteit Brussel, Brussels, B...