Peter B. Bach, MD, MAPP Department of Epidemiology and Biostatistics Memorial Sloan-Kettering Cancer Center New York, New York James R. Jett, MD Division of Pulmonary Medicine and Oncology Mayo Clinic Rochester, Minnesota Ugo Pastorino, MD Division of Thoracic Surgery Istituto Tumori Milan, Italy Melvyn S. Tockman, MD, PhD Department of Cancer Prevention and Control Moffitt Cancer Center Tampa,...

Magnetic resonance (MR) acoustic scanner noise may negatively affect the performanceof functional magnetic resonance imaging (±MRI), a problem that worsens at the higher field strengths proposed to enhance ±MRI. We present an overview of the current knowledge on theeffects of confounding acoustic MR noise in fMRI experiments. The principles and effectivenessof various methods to red...

As I sat writing this ‘personal reflections’ manuscript in the spring of 2015, I was seeing press reports related to the use of tobacco to make an Ebola therapeutic called ZMapp. For several months newspaper articles, radio shows and hour-long TV documentaries have given the public unprecedented exposure to the fact that ‘plant-made pharmaceuticals’ (PMP) can be life-saving drugs. I have been a...

Martingale decomposit ion techniques are used to derive Markovian models for the error in smoothed estimates of processes described by linear models driven by white noise. These models, together with some simple Hilbert space decomposit ion ideas, provide a simple unified framework for examining a variety of problems involving the efficient assimilation of spatial data, which we refer to as map...