The pendant-arm macrocycle, meso-5,5,7,12,12,14-hexamethyl-1,4,8,11tetraazacyclotetradecane-1,8-di-(1-methylnaphthalene) has been synthesized and its single crystal structure determined. The molecule crystallizes in a primitive monoclinic cell, with the space group P21/a (#14). The cell dimensions are a = 10.778(3)Å, b = 13.809(3) Å, c = 11.420(2) Å, ∃ = 102.49(2)°, volume = 1659.5(6) Å.

A concise total synthesis of the plant alkaloid (±)-leuconolam (1) has been achieved. A regio- and diastereoselective Lewis-acid mediated allylative cyclization was used to establish, simultaneously, two adjacent tetrasubstituted carbon centers. Furthermore, an essential arene cross-coupling to a hindered haloalkene was enabled by the use of a novel 2-anilinostannane.

The thermal properties and rheological behaviors of polystyrene (PS)-based thermoplastics bearing polyhedral oligosilsesquioxane (POSS) were investigated with variation of isobutyl (iBu)-POSS weight percentage. The incorporation of POSS-group significantly decreases the glass transition temperature and the rubbery plateau modulus. These findings are attributed to an influence of the nanometer-s...

Helical polymer brushes with a preferred-handed helix-sense composed of a poly(phenylacetylene) backbone and poly(phenyl isocyanate) pendants are synthesized. The helix-sense of the backbone is effectively controlled by the helical chirality of the pendants, which is triggered by an optically active group introduced at the pendant terminal.

The complete mol-ecule of the title compound, C32H28N2, is generated by crystallographic inversion symmetry. The dihedral angles between the central aromatic ring and the pendant adjacent rings are 61.37 (16) and 74.20 (14)°. The N-H group does not participate in hydrogen bonds and there are no aromatic π-π stacking inter-actions in the crystal.

The title compound, C(21)H(25)NO(2)S, consists of a five-membered heterocyclic ring, with pendant phenyl groups, an isopropyl group and a thio-ether residue. The thio-ether bonds to the heterocycle via the N atom. The absolute configuration results from an inversion of the configuration of substrate during the synthesis.

The purpose of this study was to determine whether the gamma-S of nucleoside thiotriphosphates and the non-bridging sulfur of internucleotide phosphorothioate diesters possess sufficient thiol character to form adducts with maleimides. Adenosine triphosphate gamma-S (ATPS) and thymidyl-PS-thymidine (TPST) were each reacted with the reporter molecule N-1 pyrene maleimide (PM) and the fluorescenc...

The maleimide motif is widely used for the selective chemical modification of cysteine residues in proteins. Despite widespread utilization, there are some potential limitations, including the irreversible nature of the reaction and, hence, the modification and the number of attachment positions. We conceived of a new class of maleimide which would address some of these limitations and provide ...

The concept of pendant tree-connectivity was introduced by Hager in 1985. For a graph G = (V,E) and a set S ⊆ V (G) of at least two vertices, an S-Steiner tree or a Steiner tree connecting S (or simply, an S-tree) is a subgraph T = (V ′, E ′) of G that is a tree with S ⊆ V ′. For an S-Steiner tree, if the degree of each vertex in S is equal to one, then this tree is called a pendant S-Steiner t...