Microsatellite repeat and single nucleotide polymorphisms (SNPs) are abundant sources of genetic variation, but existing methodologies cannot simultaneously detect these variants in a facile or inexpensive way. We describe herein a thin-film biosensor chip based on an allele-discriminating oligonucleotide array that enables genotyping for both microsatellite repeats and SNPs in a single analysi...

the children aged under 5 years from vast african areas badly suffer from falciparum malaria and many of them die of this disease. therapeutic efficacy of anti-malaria drugs, especially pyrimethamine-sulfadoxine (ps) and chloroquine (cq) to falciparum malaria is frequently evaluated and reported in recent 10 years. unfortunately, to date, these widespread materials and researches have not been ...

This study is motivated by the development of a blood cell filtration device for removal of malaria-infected, parasitized red blood cells (pRBCs). The blood was modeled as a multi-component fluid using the computational fluid dynamics discrete element method (CFD-DEM), wherein plasma was treated as a Newtonian fluid and the red blood cells (RBCs) were modeled as soft-sphere solid particles whic...

Kerteszia cruzii [former Anopheles ( ) ] is a bromeliad mosquito widespread in the Brazilian Atlantic rainforest. In South-eastern Brazil, it plays an important role malaria transmission because was infected with at least four Plasmodium species. There robust evidence that Ke. species complex. We used single nucleotide polymorphisms (SNPs) from nextRAD sequence (nextera-tagmented, reductively a...

Introduction: In spite of public health level improvement in Iran, Malaria is still an important health problem in the southeast corner of the country. Mapping distribution of endemic diseases with their relations to geographical factors has become important for public health experts. This study was carried out to provide the distribution maps of the geographical pathology of Malaria in Iran wi...

with the publication of one complete edition of the journal expedition in 1989 on hasanlu project by american archaeologists, engaged there during pre-revolutionary period, the present study highlights some of the accepted mistakes in the explanation and interpretation of the facts in the articles of that journal on one hand, and the beginning of the activities by iranian archaeologists in 2000...

background: the malaria early warning system is defined as the use of prognostic variables for predicting the occurrence of malaria epidemics several months in advance. the principal objective of this study was to provide a malaria prediction model by using meteorological variables and historical malaria morbidity data for malaria-en­demic areas in south eastern iran. methods: a total of 2002 l...

background over the past years, the malaria elimination program has considerably decreased the malaria indigenous cases and confined their incidence to the southeastern areas of iran encompassing 28 less developed counties with favorable transmission conditions. objectives the aim of the study was to investigate the effects of climatic and socioeconomic indicators on malaria transmission and to...

Malaria is a contagious infectious disease that still threatening human life. morbidity when viewed by province shows Eastern Indonesia the area with highest Annual Parasite Incidence (API), namely Papua, West NTT, and Maluku. This concern for continued efforts to control eliminate malaria in these high malaria-endemic areas. There are many strategies help prevent, include possibility of innova...