WHO estimates that as many 300 to 500 million people are infected with malaria each year. There around 3 severe cases (complicated malaria) and deaths due malaria. Other sources revealed 1.5 2.7 die every year, especially children pregnant women. Malaria is a disease emerging continues affect the of Aceh. in pregnancy serious problem considering its effects on mother fetus, which can increase m...

Malaria is a parasitic disease with limited chemotherapy options. Chemotherapy options are limited; moreover, drug resistant frequently occurs. The speed of drug development should be faster to overcome the emerging drug resistance. In the current study, a series of quinolone derivatives were subjected to quantitative structure activity relationship to identify the ideal physicochemical charact...

Malaria remains o n e o f the leading causes of morbidity and mortality in tropical countries, and the alarming spread of the drugs resistant malaria parasite underscores the need to develop new antimalarial compounds. In this study, the phytochemical constituents, in vivo antiplasmodial, and cytotoxic activity of methanolic extracts of Achyranthes aspera and Ficus thoningii were evaluated usin...

Background: Malaria is an infectious disease caused by the protozoan Plasmodium, accounting for 36% of under-five mortality. About 4.5% all malaria-infected children reported at least one symptom severe malaria, with worsening outcome. COVID-19 and malaria shared similar clinical presentation in this similarity may lead to delay initiation treatment progression from uncomplicated forms conseque...

abstract background: hypoglycaemia is a well recognized complication of falciparum malaria in children but its diagnosis may be overlooked because all the clinical features may be mimicked by severe malaria. to determine the prevalence of hypoglycaemia at the point of hospital admission of under-fives with falciparum malaria and identify its risk factors in patients seen in a nigerian secondary...

a case control study was performed in three districts in hormozgan province in 2001 to assess how different determinants affect on malaria morbidity. it assume that results will help the decision makers in all levels of national development program. a total of 384 febrile patients with positive peripheral blood smear were selected as case group, and 753 people with negative peripheral blood sme...

background: the aims of this study was to analysis the current situation of malaria and to find the distribution of anopheline mosquitoes, as probable vectors of the disease, in qom province , central iran. methods: this study was carried out in two parts. first stage was data collection about malaria cases using recorded documents of patients in the province health center, during 2001–2008. th...

background: interleukin 18 (il-18) exerts pleiotropic roles in many inflammatory-related diseases including parasitic infection. previous studies have demonstrated the promising therapeutic potential of modulating il-18 bioactivity in various pathologi­cal conditions. however, its involvement during malaria infection has yet to be established. in this study, we demonstrated the effect of modula...

Coronavirus disease 2019 (COVID-19) was first emerged in Wuhan, China in December 2019, and on March 11, 2020, WHO announced COVID-19 outbreak as a pandemic. Because chloroquine is now one of the mainstay therapies of COVID-19 all over the world, we assumed that it may play a role in preventing COVID-19 in malaria-endemic countries. So, we decided to compare the distribution map of COVID-19 wit...