The histone variant macroH2A1 contains a carboxyl-terminal ∼30-kDa domain called a macro domain. MacroH2A1 is produced as one of two alternatively spliced forms, macroH2A1.1 and macroH2A1.2. While the macro domain of macroH2A1.1 can interact with NAD(+)-derived small molecules, such as poly(ADP-ribose), macroH2A1.2's macro domain cannot. Here, we show that changes in the alternative splicing of...

In order to achieve the interoperability of heterogeneous database systems, a semantics-preserving translation of the modeling constructs and constraints captured by different data models and defined in different schemata is a necessity. It is difficult to translate the constructs and constraints of one model directly into those of another model because 1) their terminologies and modeling const...

This paper describes a supervised machine learning approach for identifying heart disease risk factors in clinical text, and assessing the impact of annotation granularity and quality on the system's ability to recognize these risk factors. We utilize a series of support vector machine models in conjunction with manually built lexicons to classify triggers specific to each risk factor. The feat...

sense a robust geographical commonality. The northern and southern boundaries of the Macro-Sudan belt apply to the different features regularly and thus seem to be more or less stable; movements across them appear to be associated with a change in profile on the part of the linguistic population (cf. the cases of Chadic and Bantu with regard to the presence or absence of features). As opposed t...

Objective: Soil organic carbon has been the most important soil quality measurement factors and has intense relation with soil physical, chemical and biological characteristics. Organic matter and its components are important factors of soil aggregates constitution and stability and play significant role in its structure. So, this research has been done for achieving this purpose. Methods: This...

Background: The imbalance between job demand and controls is associated with physical and mental disorders. The Work Design Questionnaire (WDQ) is one of the newest tools for macro-ergonomics evaluation of organizations and workplaces. In this research, the reliability and validity of the Persian WDQ (PWDQ) in the evaluation of occupational accident management and safety promotion in Persian-la...

Background: Entrepreneurship as a pillar of the development process in society derives from a socio-cultural context and ethics as a dimension of culture has a vibrant role in entrepreneurship. Therefore, the present study was designed to identify the factors that influence ethical entrepreneurial intention.  Method: A qualitative research approach was conducted using the data base method. The...

There are varieties of factors which can affect wool (macro and micro elements of wool) in sheep directly or indirectly. Genetic and environmental factors are major factors influencing wool quality and quantity. There are some bacterial, viral, fungal and espically parasitic diseases which also affect the wool. Other factors are exogenous chemicals, hormones, weather and photo period. In the pr...

soil organic carbon has been the most important soil quality measurement factors and has intense relation with soil physical, chemical and biological characteristics. organic matter and its components are important factors of soil aggregates constitution and stability and play significant role in its structure.so, this research has been done for achieving this purpose. this area is arounding sa...