BACKGROUND Rapid growth (RG) in early childhood has been associated with increased risk of obesity. The specific intervals when risk is highest have not been well examined and may help identify modifiable risk factors. OBJECTIVE To determine the correlation between RG in consecutive time intervals during the first 2 years of life with obesity at 4-5 years. METHODS This was a retrospective s...

BACKGROUND In the United Kingdom Mycobacterium kansasii is the most common pulmonary non-tuberculous mycobacteria to cause disease in the non-HIV positive population. METHODS The clinical features, treatment, and outcome of 47 patients (13 women) of mean (SD) age 58 (17) years with culture positive pulmonary M kansasii infection were compared with those of 87 patients (23 women) of mean (SD) ...

OBJECTIVE The goal was to improve immunosuppressant adherence for pediatric patients with orthotopic liver transplants by using text messaging (TM). METHODS A prospective study of sending TM reminders to the primary medication administrator (patient or caregiver) for pediatric transplant recipients was performed. Patient records were reviewed, comparing the year before and the year of the stu...

Adalimumab is a well-tolerated and effective biologic treatment for psoriasis. Given its efficacy biosimilar availability, it often first-line biologic. Clinical trial data have demonstrated that dose escalation from fortnightly to weekly an safe strategy. However, real-world lacking; therefore we aimed assess patient response in the clinical setting. We reviewed records of patients treated wit...

Results Since 2000 there have been 6 paediatric patients transplanted with ANCA GN (5 MPA). 5 patients were ANCA positive at diagnosis: 1 c-ANCA, PR3 positive and 4 pANCA MPO positive. Age at ANCA GN diagnosis was 10.4 ± 4.3 (Mean ± SD) years (range 4.1 to 15.4). eGFR at diagnosis was 14.1 ± 6.2 ml/min/1.73 m. Renal biopsy category was crescentic in 4 and sclerotic in 2 by the new histopatholog...

The question of monitoring patients taking anticonvulsants has been reviewed previously. During carbamazepine monotherapy, complete blood counts (CBC) and alanine transaminase (ALT) were measured at intervals in 23 children attending a Pediatric Neurology clinic during 1990 and 1991. The results were reviewed retrospectively. The mean age was 10.3 years (SD 3.7 yrs). Prior to starting carbamaze...

5 Abstract The present dissertation aimed at answering an important research question with support of three experimental studies: Is it possible to reduce typical AttentionDeficit/Hyperactivity-Disorder (ADHD) symptom behavior through strategies that improve intentional self-regulation? Thus, are ADHD children able to form if-then plans (implementation intentions) and do these plans enhance the...

We examined whether very preterm (< or =30 weeks gestation) children at early school age have impairments in executive function (EF) independent of IQ and processing speed, and whether demographic and neonatal risk factors were associated with EF impairments. A consecutive sample of 50 children (27 boys and 23 girls) born very preterm (mean age = 5.9 years, SD = 0.4, mean gestational age = 28.0...

OBJECTIVES The aim of the present study was to assess the effects of aluminum (Al) on the nervous system functions in workers chronically exposed to Al. MATERIALS AND METHODS The study covered a selected group of 67 male workers (mean age, 38.7 SD 10.3 years; range 23-55 years) involved in the Al production. Their employment duration ranged between 2 and 34 years (mean, 14.6 SD 8.9 years). Al...