The study was conducted to evaluate carcass yield and chemical composition of thigh and breast muscles of broilers fed three different lysine requirement levels: high lysine (+10% NRC), standard (NRC) and low lysine (-10% NRC) and two ways of expressing amino acids in feedstuffs (total or digestible amino acids). The results of this study showed that diet formulation based on digestible amino a...

We conducted three experiments to determine the effects of increasing L-lysine HCl in growing-finishing pig diets. Experiments 1 and 2, conducted at the Kansas State University research center, each used 360 growing-finishing pigs with initial BW of 56 and 63 kg, respectively. Dietary treatments were sorghum- (Exp. 1) or corn- (Exp. 2) soybean meal-based and consisted of a control (no L-lysine ...

Lysine methyltransferase which catalyze methylation of histone and non-histone proteins, play a crucial role in diverse biological processes and has emerged as a promising target for the development of various human diseases, including cancer, inflammation, and psychiatric disorders. However, inhibiting lysine methyltransferases selectively has presented many challenges to medicinal chemists. D...

Lysine is considered an 'essential amino acid' required at sufficient levels to prevent malnutrition and serious diseases, particularly in developing countries. It is mostly obtained from various plant foods. In the current issue (pages 4285–4296) Yang and colleagues report on successful stimulation of lysine biosynthesis and suppression of its catabolism in transgenic rice plants without chang...

We have previously reported that weanling rats fed a 20% wheat gluten diet, limiting in lysine and containing no detectable carnitine, have significantly lower levels of carnitine in skeletal and heart muscle than rats receiving adequate dietary lysine. Rats on 20% wheat gluten diets were administered appropriate levels of DL-[6-i*C]lysine, L-[mefhyZ3H]methionine, t-N-[mefhyZ-3H]trimethyl-L-lys...

Lysine as an essential amino acid supplemented to fulfil the dietary requirement of Poultry feed. In Pakistan all this demand is accomplished by importing lysine for feed sector. Wild Brevibacterium flavum was used to induce mutation by random mutagenesis for hyper production of lysine through fermentation. The highest lysine producing strain (BFENU2) was screened with 21.64 g/L production by m...

BACKGROUND Feline herpesvirus 1 is a highly contagious virus that affects many cats. Virus infection presents with flu-like signs and irritation of ocular and nasal regions. While cats can recover from active infections without medical treatment, examination by a veterinarian is recommended. Lysine supplementation appears to be a popular intervention (recommended by > 90 % of veterinarians in c...

The uptake of the basic amino acids arginine, ornithine, and lysine was studied in membrane vesicles derived from cells of Lactococcus lactis which were fused with liposomes in which beef heart mitochondrial cytochrome c oxidase was incorporated as a proton motive force (PMF)-generating system. In the presence of ascorbate N,N,N'N'-tetramethylphenylenediamine-cytochrome c as the electron donor,...

An experiment was performed to evaluate the effects of dietary metabolizable energy (ME) and lysine on carcass characteristics and meat quality in Arbor Acres (AA) broilers from 1 to 56 days of age. A total of 2,970 1-d-old male broiler chicks were randomly allocated to nine dietary treatments (three ME levels in combination with three lysine levels), and dietary ME and lysine concentrations we...