DLBCL (diffuse large B-cell lymphoma) is the most common subtype of non-Hodgkin's lymphoma. Current therapy for patients includes chemotherapy and monoclonal antibodies. Although oncogene-targeted therapy is dramatically successful for patients with certain kinds of leukaemias, there are no such agents yet for DLBCL. One reason for this is that several key oncogenes involved in DLBCL pathogenes...

background:   primary bone lymphoma or non-hodgkin lymphoma of bone is a rare disease. there are only a few case series of stage ie of this condition in medical literature. the aim of this study is to determine the rate of survival   for stage ie after combined modality treatment, the rate of local recurrence, and the results of limb salvage in cases   of local recurrence.     methods:   we col...

BACKGROUND & AIMS There is controversy over whether the treatment of patients with ulcerative colitis (UC) with thiopurines increases their risk of lymphoma. We evaluated the risk of lymphoma (ongoing, residual, and per year of therapy) among thiopurine-treated patients with UC. METHODS We obtained nationwide data from the Veterans Affairs (VA) health care system from 2001 to 2011. We perform...

Peripheral T-cell lymphoma, not otherwise specified (PTCL-NOS) is a heterogeneous category of nodal and extranodal mature T-cell lymphomas. PTCL-NOS is a highly aggressive lymphoma, and its prognosis is poorer than those of aggressive B-cell lymphoma such as diffuse large B-cell lymphoma(DLBCL). Current standard chemotherapies for aggressive B-cell lymphoma, such as CHOP, are the commonly used ...

Localized Nodular Lymphocyte Predominant Hodgkin Lymphoma is a rare disease with an overall good prognosis but frequent late relapses. Due to it's rarity there is no standard therapeutic approach and pathological diagnosis may be hard. In this paper we discuss the technical aspects of the radiation therapy and histological issues. The new fields reductions proposed for classical Hodgkin lymphom...

Patients with diffuse lymphoblastic lymphoma (which includes convoluted lymphocytic lymphoma) with mediastinal involvement have predictable progression of disease to a leukemic phase that is cytologically indistinguishable from acute lymphoblastic leukemia (ALL). Therefore we treated 12 patients with diffuse lymphoblastic lymphoma involving the mediastinum with therapy that is effective in ALL....

Acute renal failure (ARF) is an unusual manifestation of lymphomatous infiltration of the kidneys. In this article, a patient whose initial presentation of lymphoma was the sudden onset of painless hematuria and ARF is described. The absence of other causes of ARF, together with massively enlarged unobstructed kidneys on renal ultrasonography, strongly suggested an infiltrative process. Renal b...

OBJECTIVE Although the use of 18F-fluorodeoxyglucose (FDG) PET for evaluating lymphoma is gaining in popularity, PET is not yet universally available and large prospective comparisons between 67Ga and 18F-FDG PET scans in predicting the long-term outcome after treatment are lacking. Scintigraphic imaging with 67Ga remains an important tool in evaluating the response of lymphoma to therapy. Ther...

Mediastinal radiation is commonly used to treat Hodgkin's and non-Hodgkin's lymphoma, lung and breast cancer. Cardiac complications after radiation therapy are well described, although rare. A large spectrum of injuries can occur, causing long term morbidity among survivors. We describe a case of post-actinic ascending aortic wall thickening that prevented saphenous vein proximal anastomosis an...

Purpose: To demonstrate a rare clinical case of early recurrence verified primary genital lymphoma and the possibility 99mTc-1-Thio-D-glucose (99mTc-TG) SPECT/CT using to brain metastasis diagnosis. Material methods: A patient with diagnosis diffuse large B-cell underwent magnetic resonance imaging (MRI) assess extent disease. Post-treatment follow-up included 18F-FDG PET/CT. diagnose metastasi...