نتایج جستجو برای: lung infection
تعداد نتایج: 744823 فیلتر نتایج به سال:
INTRODUCTION Probiotic use to prevent nosocomial gastrointestinal and potentially respiratory tract infections in critical care has shown great promise in recent clinical trials of adult and pediatric patients. Despite well-documented benefits of probiotic use in intestinal disorders, the potential for probiotic treatment to reduce lung injury following infection and shock has not been well exp...
Experimental chronic pneumonia was established in normal BALB/c mice employing a virulent encapsulated strain of Klebsiella pneumoniae B5055. A single exposure to the bacterial pathogen resulted in acute pneumonia that resolved within a week. To achieve the chronic state of lung infection, repeated infection was given via intranasal route. Mice were inoculated with 50ul of 10 4 CFU/ml each on d...
BACKGROUND Patients with COPD are at risk of non-tuberculous mycobacterial infection (NTM). This study examined the histology of lung tissue from COPD patients following lung volume reduction with particular focus on evidence of mycobacterial infection. METHODS Retrospective histological study of 142 consecutive lung volume reduction surgical specimens (126 separate patients) at Royal Brompto...
Think outside the box: extrapulmonary manifestations of severe respiratory syncytial virus infection
Extrapulmonary effects of severe respiratory syncytial virus (RSV) infection are not uncommon. Dr Eisenhut's systematic review of extrapulmonary manifestations of severe RSV infection clearly demonstrates clinical consequences peripheral to the lung parenchyma. The extrapulmonary impact of RSV infection raises questions as to whether these are direct RSV effects (i.e., RSV infection of site-spe...
BACKGROUND Inhibitors of mTOR, such as sirolimus, have been shown to induce thymus involution and inflammatory lung disease in mice. The latter effect supports the role of this serine/threonine kinase in ameliorating lung inflammation. Other studies have shown sirolimus reduces/delays lung disease associated with various strains of influenza A virus (IAV). Thus, the effects of mTOR inhibitors o...
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