background : ovarian cancer is the leading cause of death among gynecological cancers. changes in the methylation of brca1 and brca2 may be an effective mechanism for breast and ovarian cancer. this study evaluates the protein expression and methylation status of brca2 in iranian patients. methods : we assessed 60 mullerian-type ovarian cancers by methylation-specific pcr assays and immunohisto...

objective(s): although low-dose radiotherapy (rt) that involves low collateral damage is more suitable for hepatocellular carcinoma (hcc) than traditional high-dose rt, but to achieve satisfactory therapeutic effect with low-dose rt, it is necessary to sensitize hcc cells to irradiation. this study was aimed to determine whether radiosensitivity of hcc cells can be enhanced using mir-26b by tar...

Objective: The aim of this study was to compare the three endurance training intensities on the expression of Perlipin A protein in subcutaneous adipose tissue and pancreatic B-cells function in male diabetic rats. Materials and Methods: In this study, 40 healthy male wistar rats were divided into five groups, including diabetic with low intensity endurance training, diabetic with moderate int...

Background & objective: The current study aimed to perform an immunohistochemical analysis of patterns of apoptotic and cell proliferative related protein expression in different histological grades and immune phenotypes of malignant lymphomas and other lymphoproliferative disorders Methods:This observational study was carried o...

seed protein profiles of 47 accessions belonging to eleven species and four tribes of grain legumes were studied, by extracting the total proteins from ten single seeds in each accession and performing sds-polyacrylamide gel electrophoresis. all eleven species were clearly recognizable from their protein banding patterns, but only phaseolus vulgaris expressed high intraspecific variations, ...

Abstract Background and Aims Low-protein diet is considered crucial in patients with chronic kidney disease to slow down function deterioration control metabolic variables such as serum phosphate, urea bicarbonate. However, low-protein may result malnutrition if do not respect nutritional prescription. Thus, the present study examined risk of protein CKD who started a diet. Method We analysed a...