We present a case of small bowel diverticulum with gastrointestinal stromal tumor (GIST). This GIST in the diverticulum was confirmed by immunohistochemistry and was of low-grade malignant potential.

Taxol is a promising agent for use in ovarian cancer and other malig nancies. One problem associated with taxol is its low aqueous solubility, requiring Cremophor EL (polyethoxylated castor oil) and ethanol as ex cipients (Diluent 12); these agents cause serious adverse effects. Liposomes containing taxol and phospholipid (in a 1:33 mole ratio, respectively) were prepared from phosphatidylglyce...

The cytotoxic activity of ethanolic extracts of Thymus vulgaris, Thuja orientalis and Achillea millefolium was investigated on various growing tumor cell lines. MTT colorimetric assay was used for measuring the inhibition of cell proliferation. All of the three extracts showed a relatively dose-dependent inhibition of proliferation of human breast cancer (SK-Br-3, MDA-MB-435) and leukemia ...

TASK-3, a two-pore-domain (K2P) potassium channel, has been implicated as important regulator for the effector function and proliferation of T-cells. Interestingly, TASK-3 has also a functional impact on tumor cells. Therefore, we sought to investigate whether TASK3 modulation might have a therapeutic potential for malignant gliomas by a variety of phenotypical and functional in vitro assays mi...

Physical examination and mammography are currently the only proven and reliable methods of early detection of breast cancer. Although, both procedures are highly sensitive, their limited specificity often requires surgical biopsy in order to differentiate between malignant and benign lesions.Palpable mass abnormalities of breast are often difficult to evaluate mammographically, especially in pa...

The spectrum of uterine smooth muscle cell tumours (SMT) ranges from leiomyomas to leiomyosarcomas (LMS). Atypical (AL) are a SMT contentious nature due its indeterminate malignant potential. Although the risk recurrence is low there limited experience on management. On other hand, it generally believed that LMS arises de novo, rather than precursor lesion.