the Cochrane review, with its emphasis on randomized controlled trials, does not advocate universal application of HBO2 to delayed radiation injuries. In the United States, third-party insurance entities will frequently reimburse for this application, but often a formal appeal will be required to obtain payment. In informal surveys of HBO2 practitioners at continuing medical education meetings ...

Introduction Given the fact that children are more sensitive to radiation, compared to adults, special attention needs to be paid to radiation protection in pediatric radiology. Diagnostic reference level (DRL) has been defined to be employed as a practical tool for examining the overall performance of a radiological center in terms of patient dose among a series of similar equipments in an are...

BACKGROUND Acute radiation-induced liver injury is a limitation for hepatoma radiotherapy. Come so far the clinical treatments are insufficient. The effective, specific, low toxicity and novel drugs are in powerful need. Glibenclamide is a common hypoglycemic. Some studies have revealed its relation with intracellular reactive oxygen species, the crucial mediator to radiation injury. This study...

Whole-brain irradiation (WBI) represents the primary mode of treatment for brain metastases; about 200 000 patients receive WBI each year in the USA. Up to 50% of adult and 100% of pediatric brain cancer patients who survive >6 months post-WBI will suffer from a progressive, cognitive impairment. At present, there are no proven long-term treatments or preventive strategies for this significant ...

1 Laboratory of Radiation Exposure & Therapeutics, National Radiation Emergency Medical Center, Korea 8 Institute of Radiological and Medical Sciences, 75 Nowon-ro, Nowon-gu, Seoul 01812, Republic of Korea 9 2 Department of Pathology, Korea Cancer Center Hospital, Korea Institute of Radiological and Medical Sciences, 10 75 Nowon-ro, Nowon-gu, Seoul 01812, Republic of Korea 11 *Correspondence: E...

Background & Aims Radiation therapy in the pelvic area is associated with side effects that impact the quality of life of cancer survivors. Interestingly, the gastrointestinal tract is able to adapt to significant changes in oxygen availability, suggesting that mechanisms related to hypoxia sensing help preserve tissue integrity in this organ. However, hypoxia-inducible factor (HIF)-dependent r...