AIMS We aimed to evaluate the prognostic significance of histopathological patterns of seminal vesicle invasion (SVI) after radical prostatectomy. METHODS AND RESULTS Seminal vesicles of 1050 radical prostatectomy specimens from the Karolinska Hospital, from 1998 to 2005, were reviewed. Extraprostatic SVI was found in 60 cases (5.7%). Associations between histopathological characteristics of ...

The interrelationship among localization of tumor, local extension, lymph node metastasis and various histological grades was investigated in 31 consecutive series of prostate cancer treated by radical prostatectomy. Surgical specimens were examined by step sections cut perpendicular to the urethra. Each tumor was graded histologically in accordance with WHO-Mostofi grading (evaluated by nuclea...

Abstract. In this paper, a predator-prey-disease model with immune response in the infected prey is formulated. The basic reproduction number of the within-host model is defined and it is found that there are three equilibria: extinction equilibrium, infection-free equilibrium and infection-persistent equilibrium. The stabilities of these equilibria are completely determined by the reproduction...

AIM Rectal carcinoid is a rare rectal tumour with a good prognosis. The aim of this study was to assess its clinicopathological characteristics and prognostic factors in a single institution. METHOD Clinical and pathological information was retrospectively collected in a single institution, and patients' outcomes were determined. Multivariate analyses were performed to find independent progno...

The invasion of alien plants into the territory Georgia started in ancient times and continues today. Sicyos angulatus L., a species North American origin, is an example such invasion. first established populations S. occurrence were observed 2012. Since then, new localities have been recorded, both agricultural disturbed natural communities. species, which has easily adapted to local soil clim...

Invasion of the tunica albuginea (TA) and/or urethra are key factors in determining feasibility organ-preserving surgery penile cancer (PC). Magnetic resonance imaging (MRI) appeared to be a promising technique for preoperative local staging. We performed systematic review (SR) and pooled meta-analysis investigate diagnostic performance MRI staging primary PC. An SR up May 2021 was according PR...

Cells generate mechanical force to organize the extracellular matrix (ECM) and drive important developmental and reparative processes. Likewise, tumor cells invading into three-dimensional (3D) matrices remodel the ECM microenvironment. Importantly, we previously reported a distinct radial reorganization of the collagen matrix surrounding tumors that facilitates local invasion. Here we describe...

PURPOSE Epigallocatechin-3-gallate (EGCG) is an antioxidant agent derived from green tea. Because it has chemopreventive and anti-invasive effect against various cancer cells, EGCG can be used to inhibit proliferation and invasion of cholangiocarcinoma (CCA) cells. METHODS The anticancer effects of EGCG were studied using human CCA cells (HuCC-T1). Apoptosis was analyzed by Western blotting. ...

OBJECTIVES We evaluated the clinical benefit of segmentectomy for patients with cT1bN0M0 lung cancer. METHODS We retrospectively reviewed the medical records of 178 patients who underwent lobectomy or segmentectomy for cT1bN0M0 lung adenocarcinoma and squamous cell carcinoma from January 1995 to December 2005. We investigated the association of surgical outcomes with the presence of pathologi...

BACKGROUND Tongue cancer is one of the common cancers in head and neck region. Cervical node metastasis is the strongest poor prognostic factor. Other prognostic factors were also said to be of significance. Our aim was to find out the significant prognostic factors of tumor aggressiveness in Indian perspective. MATERIAL AND METHODS Sixty cases of early cancer of oral tongue with clinically n...