OBJECTIVE To investigate socioeconomic inequalities in outcome of pregnancy associated with Down syndrome (DS) compared with other congenital anomalies screened for during pregnancy. DESIGN AND SETTING Retrospective population-based registry study (East Midlands & South Yorkshire in England). PARTICIPANTS All registered cases of DS and nine selected congenital anomalies with poor prognostic...

Two university centers in Debrecen, Hungary and Seoul, Republic of Korea collaborated in a prospective study of fertility following induced abortion. Conception rates were compared for 30 months among two groups of women whose last pregnancy outcome was either an induced abortion or a live birth. The cumulative life-table pregnancy rates at each six-month interval for the 30 months of the study...

BACKGROUND/AIMS We sought to investigate the association between preconception serum lipids and their daily rate of change in relation to length of gestation. METHODS In a cohort of 70 women, 61 (87%) became pregnant, resulting in 48 (69%) live births. Serum lipid measurements (in milligrams per deciliter) included total cholesterol, free cholesterol, triglycerides and phospholipids at precon...

BACKGROUND Both cleavage-stage and blastocyst-stage embryo transfer policies have advantages and drawbacks. The number of embryos transferred, however, is a crucial parameter that needs to be considered before attempting any comparison. METHODS An extensive literature search yielded initially 282 studies from which 8 randomized controlled trials met the inclusion criteria: (i) truly randomize...

BACKGROUND The effectiveness of aromatase inhibitors (AIs) in the treatment of anovulatory polycystic ovary syndrome (PCOS) remains unclear. The objective was to determine whether AIs are effective in improving fertility outcomes in women with PCOS. METHODS Databases were searched until July 2011. Inclusion criteria were women with PCOS, who are infertile, receiving any type, dose and frequen...

BACKGROUND There seems to be little discussion between patient and physician about the use of complementary and alternative medicines (CAMs), perhaps because they are not perceived to have adverse effects on fertility. We therefore compared ongoing pregnancy and live birth rate in spontaneous users and non-users of CAM during a 12-month period of assisted reproduction technique (ART) treatment....

Recurrent pregnancy loss (RPL), recurrent miscarriage or habitual abortion is a multifactorial problem with exasperating and challenging aspects in reproductive medicine. It is defined as two or more consecutive loss of clinical pregnancies. However, the incidence of RPL is less than 5% in pregnant women but its etiology is diverse and varied and also for more than 50% of cases is not clearly d...

OBJECTIVES To look retrospectively at patients undergoing elective, ultrasound indicated and rescue cervical cerclage, examine the immediate pregnancy outcomes and compare them. DESIGN This was a retrospective observational study using the maternity and neonatal databank to identify patients having cervical cerclage between 1985 and 2009 inclusive. Data extracted included patient demographics...

INTRODUCTION This study is part of a longitudinal cohort undertaken in both women and men to describe live birth outcome after undergoing assisted reproductive technology (ART) treatment in a clinical setting. Another objective was to follow women and men living with children from other alternatives after ART, such as adoption. MATERIAL AND METHODS A total of 439 (80.5%) women and 423 (77.6%)...

Background: Despite the large number of papers published on the efficiency of different exogenous gonadotropins, no confirmed protocol exists. Therefore, the aim of the present study was to compare the efficacy of 4 exogenous gonadotropins in IVF/ICSI cycles.Methods: This study, performed from January 2014 to May 2014, recruited 160 women referred to Ghadir Mother and Child Hospital and Dena Ho...