This study aims to evaluate the occurrence of food allergy peanuts in atopic dermatitis (AD) patients and analyse sensitization molecular components. The complete dermatological allergological examination including components with Multiplex ISAC testing was performed. Altogether 100 AD were examined – 48 men, 52 women, average age 40.9 years. confirmed 27% patients; majority these are sensitize...

PURPOSE The extent of palmitate uptake by hepatocytes is dependent upon the surface charge of the extracellular binding protein. Specifically, hepatocyte uptake is greater when palmitate is bound to cationic binding proteins than when it is bound to anionic proteins. To further understand the role of protein surface charge on the uptake process of protein-bound ligands, we examined the rate of ...

Among amphitropic proteins, human glycolipid transfer protein (GLTP) forms a structurally-unique fold that translocates on/off membranes to specifically transfer glycolipids. Phosphatidylcholine (PC) bilayers with curvature-induced packing stress stimulate much faster glycolipid intervesicular transfer than nonstressed PC bilayers raising questions about planar cytosol-facing biomembranes being...

In severe COVID-19 patients the blood level of autoantibodies (IgG) to neurospecific proteins was determined. It defined marked increase in peripheral myelin protein, protein lipid S100 type 2 dopamine receptors and dopamine. At same time, it designate relationship between levels NMDA receptors. High specific IgG SARS-CoV-2 S-Trimer Protein coincided with high

Eukaryotic phosphatidylinositol transfer protein is a ubiquitous multifunctional protein that transports phospholipids between membrane surfaces and participates in cellular phospholipid metabolism during signal transduction and vesicular trafficking. The three-dimensional structure of the alpha-isoform of rat phosphatidylinositol transfer protein complexed with one molecule of phosphatidylchol...